Question · asked by 1 review
NSAID (single administration, any dose) vs paracetamol: Relief of pain
- Population
- women with perineal pain in the early postpartum period
- Intervention
- NSAID (single administration, any dose)
- Comparison
- paracetamol
- Outcome
- Relief of pain
NSAID (single administration, any dose) may leads to higher adequate pain relief (4 hours after administration) compared with paracetamol (low certainty).
What each review found
Include earlier review versionsNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
NSAID (single administration, any dose) vs paracetamol Adequate pain relief (4 hours after administration) · women with perineal pain in the early postpartum period NSAID (single administration, any dose) may leads to higher adequate pain relief (4 hours after administration) compared with paracetamol (low certainty). Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum period (2021) · Cochrane Headline outcomes only | RR 1.54 [1.07, 2.22] | 3 studies · 342 participants | Low |
NSAID (single administration, any dose) vs paracetamol Adequate pain relief (6 hours after administration) · women with perineal pain in the early postpartum period It is very uncertain whether NSAID (single administration, any dose) changes adequate pain relief (6 hours after administration) compared with paracetamol (very low certainty). Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum period (2021) · Cochrane Headline outcomes only | RR 1.82 [0.61, 5.47] | 2 studies · 99 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum period 2021 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.