Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

699 questions · 745 findings · 185 reviews

No studies found 180 · 24.2%GRADE not reported 76 · 10.2%Very low 194 · 26%Low 154 · 20.7%Moderate 110 · 14.8%High 31 · 4.2%

External control of fluoride concentration vs Not applicable

Water samples with fluoride concentration outside the acceptable range · Brazilian cities with artificially fluoridated public water supplies

After excluding Silva et al., the pooled prevalence outside the acceptable range was 47.1%.

1 finding from 1 review

External control of fluoride concentration vs Not applicable

Water samples with fluoride concentration below the acceptable range · Brazilian cities in the Southeast region with artificially fluoridated public water supplies

In the Southeast region, 24.6% of samples were below the acceptable range.

1 finding from 1 review

Rubber dam vs Isolite system

Participant acceptance/satisfaction · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)
1 finding from 1 review
  • Rubber dam isolation for restorative treatment in dental patients 2021 · Cochrane All outcomes
    Pit and fissure sealing (permanent molars)
    Rubber dam may be associated with significantly lower satisfaction than the Isolite system but evidence very uncertain, mainly worse comfort (31%, P=0.02) and less preference (26%, P=0.002) (Alhareky 2014).
    1 study · 42 participants
    Very low

Endometrial resection or ablation vs minimally invasive hysterectomy

Acceptability Proportion satisfied with treatment · heavy menstrual bleeding

Endometrial resection or ablation probably leads to lower acceptability Proportion satisfied with treatment compared with minimally invasive hysterectomy (moderate certainty).

1 finding from 1 review

Endometrial resection or ablation vs unspecified (or at surgeon's discretion) route of hysterectomy

Acceptability Proportion satisfied with treatment · heavy menstrual bleeding

Endometrial resection/ablation showed no clear difference in acceptability Proportion satisfied with treatment compared with unspecified (or at surgeon's discretion) route of hysterectomy (moderate certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

acceptability ‐ drop‐outs due to adverse events: post‐intervention · adults with long‐term physical conditions (18 years or older)

It is very uncertain whether pharmacological interventions changes acceptability ‐ drop‐outs due to adverse events: post‐intervention compared with placebo (very low certainty).

1 finding from 1 review