Cochrane · systematic review · CD008819

Graduated compression stockings for the initial treatment of varicose veins in people without venous ulceration

Knight (nee Shingler), SL, Robertson, L, Stewart, M · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
11
No studies
1
Included studies
NR
No studies 1 · 8.3%Ungraded 0 · 0%Very low 5 · 41.7%Low 6 · 50%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Compression stockings compared with no treatment or placebo stockings for the initial treatment of varicose veins without venous ulceration

Population: people with varicose veins without venous ulceration
6 questions
OutcomeEffectEvidenceStatus / GRADE
Change in symptoms (ranging from 1 week to 3 months)
Compression stockings vs no treatment or placebo stockings
no estimate extracted4 studies · 232 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Physiological measures (1 week)
Compression stockings vs no treatment or placebo stockings
no estimate extracted2 studies · 90 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Complications (1 week, 4 weeks and up to 6 weeks' postpartumc)
Compression stockings vs no treatment or placebo stockings
no estimate extracted3 studies · 148 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Compliance (1 week and up to 6 weeks' postpartumc)
Compression stockings vs no treatment or placebo stockings
no estimate extracted3 studies · 136 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Comfort, tolerance and acceptability of wearing stockings (1 week and up to 6 weeks' postpartumc)
Compression stockings vs no treatment or placebo stockings
no estimate extracted2 studies · 106 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Quality of life (3 months)
Compression stockings vs no treatment or placebo stockings
no estimate extracted1 study · 70 participantsLow
Downgraded: risk of bias, imprecision

Compression stockings compared with compression stockings for the initial treatment of varicose veins without venous ulceration

Population: people with varicose veins without venous ulceration
6 questions
OutcomeEffectEvidenceStatus / GRADE
Change in symptoms (ranging from 3 weeks to 6 months)
Compression stockings vs compression stockings
no estimate extracted5 studies · 616 participantsLow
Downgraded: risk of bias, inconsistency
Physiological measures (ranging from 15 minutes to 8 weeks)
Compression stockings vs compression stockings
no estimate extracted5 studies · 141 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Complications (ranging from 15 minutes to 6 months)
Compression stockings vs compression stockings
no estimate extracted4 studies · 541 participantsLow
Downgraded: risk of bias, inconsistency
Compliance (ranging from 6 weeks to 6 months)
Compression stockings vs compression stockings
no estimate extracted2 studies · 467 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Comfort, tolerance and acceptability of wearing stockings (ranging from 3 weeks to 6 months)
Compression stockings vs compression stockings
no estimate extracted4 studies · 578 participantsVery low
Downgraded: risk of bias, inconsistency, indirectness
Quality of life
Compression stockings vs compression stockings
no estimate extractedNRNo studies