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Evidence found and GRADE certainty

288 questions · 290 findings · 74 reviews · Headline outcomes only

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No studies found 56 · 19.3%GRADE not reported 21 · 7.2%Very low 61 · 21%Low 62 · 21.4%Moderate 39 · 13.4%High 51 · 17.6%

Intervention not reported

aMean baseline values. · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pitavastatin dose · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

mg/day · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

mg/day · participants with normal or abnormal lipid profiles
1 finding from 1 review

Antibiotics vs placebo or no treatment

Recurrence of symptomatic UTI in children · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Recurrence of symptomatic UTI in children without VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children without VUR compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Recurrence of symptomatic UTI in children with VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children with VUR compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Recurrence of symptomatic UTI in children, in studies with adequate allocation concealment · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment probably leads to lower recurrence of symptomatic UTI in children, in studies with adequate… compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Repeat positive urine culture · children with previous UTI and most do not have a renal tract abnormality such as VUR

It is very uncertain whether antibiotic treatment changes repeat positive urine culture compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Microbial resistance to prophylactic drug · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment showed no clear difference in microbial resistance to prophylactic drug compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Intervention not reported

LDL‐cholesterol fluvastatin 10 mg/day · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

Total cholesterol fluvastatin 80 mg/day · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

CI: Confidence interval · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Mean baseline values. · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

Triglycerides fluvastatin 10 mg/day · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

Triglycerides fluvastatin 20 mg/day · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

Triglycerides fluvastatin 40 mg/day · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

Triglycerides fluvastatin 80 mg/day · participants with normal or abnormal lipid profiles
1 finding from 1 review

Intervention not reported

CI: Confidence interval · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review