Findings

What do systematic reviews say?

291 questions · 293 findings · 75 reviews

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No studies found 56 · 19.1%GRADE not reported 24 · 8.2%Very low 61 · 20.8%Low 62 · 21.2%Moderate 39 · 13.3%High 51 · 17.4%

Intervention not reported

mg/day · participants with normal or abnormal lipid profiles

1 finding from 1 review

Pitavastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
36 studies · 3847 participants
High

Intervention not reported

mg/day · participants with normal or abnormal lipid profiles

1 finding from 1 review

Pitavastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 469 participants
High

Intervention not reported

CI: Confidence interval · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Pitavastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

aMean baseline values. · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Pitavastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Pitavastatin dose · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Pitavastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

mg/day · participants with normal or abnormal lipid profiles

1 finding from 1 review

Pitavastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 777 participants
High

Intervention not reported

mg/day · participants with normal or abnormal lipid profiles

1 finding from 1 review

Pitavastatin for lowering lipids 2020 · Cochrane Headline outcomes only
no estimate extracted
32 studies · 2789 participants
High

Antibiotics vs placebo or no treatment

Recurrence of symptomatic UTI in children · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children compared with placebo or no treatment (low certainty).

1 finding from 1 review

Long‐term antibiotics for preventing recurrent urinary tract infection in children 2019 · Cochrane Headline outcomes only
RR 0.75 [0.28, 1.98]
5 studies · 1074 participants
Low

Antibiotics vs placebo or no treatment

Recurrence of symptomatic UTI in children without VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children without VUR compared with placebo or no treatment (low certainty).

1 finding from 1 review

Long‐term antibiotics for preventing recurrent urinary tract infection in children 2019 · Cochrane Headline outcomes only
RR 0.6 [0.13, 2.74]
4 studies · 541 participants
Low

Antibiotics vs placebo or no treatment

Recurrence of symptomatic UTI in children with VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children with VUR compared with placebo or no treatment (low certainty).

1 finding from 1 review

Long‐term antibiotics for preventing recurrent urinary tract infection in children 2019 · Cochrane Headline outcomes only
RR 0.65 [0.39, 1.07]
2 studies · 371 participants
Low

Antibiotics vs placebo or no treatment

Recurrence of symptomatic UTI in children, in studies with adequate allocation concealment · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment probably leads to lower recurrence of symptomatic UTI in children, in studies with adequate… compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Long‐term antibiotics for preventing recurrent urinary tract infection in children 2019 · Cochrane Headline outcomes only
RR 0.68 [0.48, 0.95]
2 studies · 914 participants
Moderate

Antibiotics vs placebo or no treatment

Repeat positive urine culture · children with previous UTI and most do not have a renal tract abnormality such as VUR

It is very uncertain whether antibiotic treatment changes repeat positive urine culture compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Long‐term antibiotics for preventing recurrent urinary tract infection in children 2019 · Cochrane Headline outcomes only
RR 0.31 [0.08, 1.18]
4 studies · 467 participants
Very low

Antibiotics vs placebo or no treatment

All adverse events · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment showed no clear difference in all adverse events compared with placebo or no treatment (low certainty).

1 finding from 1 review

Long‐term antibiotics for preventing recurrent urinary tract infection in children 2019 · Cochrane Headline outcomes only
RR 2.31 [0.03, 170.67]
2 studies · 914 participants
Low

Antibiotics vs placebo or no treatment

Microbial resistance to prophylactic drug · children with previous UTI and most do not have a renal tract abnormality such as VUR

Antibiotic treatment showed no clear difference in microbial resistance to prophylactic drug compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Long‐term antibiotics for preventing recurrent urinary tract infection in children 2019 · Cochrane Headline outcomes only
RR 2.4 [0.62, 9.26]
2 studies · 118 participants
Moderate

Intervention not reported

LDL‐cholesterol fluvastatin 10 mg/day · participants with normal or abnormal lipid profiles

1 finding from 1 review

Fluvastatin for lowering lipids 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 595 participants
High

Intervention not reported

Total cholesterol fluvastatin 80 mg/day · participants with normal or abnormal lipid profiles

1 finding from 1 review

Fluvastatin for lowering lipids 2018 · Cochrane Headline outcomes only
no estimate extracted
27 studies · 3943 participants
High

Intervention not reported

CI: Confidence interval · participants with normal or abnormal lipid profiles

The review found no eligible studies for this question.

1 finding from 1 review

Fluvastatin for lowering lipids 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Mean baseline values. · participants with normal or abnormal lipid profiles

1 finding from 1 review

Fluvastatin for lowering lipids 2018 · Cochrane Headline outcomes only
no estimate extracted
1 participants
GRADE not reported

Intervention not reported

Triglycerides fluvastatin 10 mg/day · participants with normal or abnormal lipid profiles

1 finding from 1 review

Fluvastatin for lowering lipids 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 259 participants
High

Intervention not reported

Triglycerides fluvastatin 20 mg/day · participants with normal or abnormal lipid profiles

1 finding from 1 review

Fluvastatin for lowering lipids 2018 · Cochrane Headline outcomes only
no estimate extracted
39 studies · 7510 participants
High