What do systematic reviews say?

Request‐based ethics consultation vs usual care

The review found no eligible studies for this question.

• Ethical case interventions for adult patients 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Stopping feeds vs continuing feeds during transfusion

• Stopping enteral feeds for prevention of transfusion‐associated necrotising enterocolitis in preterm infants 2019 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Routine scale and polish every 6 months vs Routine scale and polish every 12 months

Routine scale and polish every 6 months showed no clear difference in oral health-related quality of life (OHIP-14) compared with routine scale and polish every 12 months (high certainty).

• Routine scale and polish for periodontal health in adults 2018 · Cochrane All outcomes

  36 months
  MD -0.40 [-1.34, 0.54]
  1 study · 786 participants
  High

Routine scale and polish at a fixed interval vs No scheduled scale and polish treatment

Planned, regular routine scale and polish (6-monthly; 12-monthly… may leads to higher participant satisfaction (perceived oral cleanliness) compared with no scheduled scale and polish treatment (low certainty).

• Routine scale and polish for periodontal health in adults 2018 · Cochrane All outcomes

  36 months · 6-monthly (12-monthly parallel)
  RR 1.83 [1.28, 2.63]
  1 study · 205 participants
  Low

Routine scale and polish provided by a dentist vs Routine scale and polish provided by a dental care professional (dental therapist or hygienist)

The review found no eligible studies for this question.

• Routine scale and polish for periodontal health in adults 2018 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Wax (fluid wax), two stage-two step selective pressure final impression vs Polysulfide rubber (elastomer)

The review found no eligible studies for this question.

• Final‐impression techniques and materials for making complete and removable partial dentures 2018 · Cochrane All outcomes
  Not measured
  0 studies
  No studies found

Biofunctional Prosthetic System (BPS): closed-mouth two stage-two step final impression with addition silicone elastomer vs Conventional complete denture technique (CCD): open-mouth two stage-two step conventional technique using elastomer

• Final‐impression techniques and materials for making complete and removable partial dentures 2018 · Cochrane All outcomes

  3 months
  OHIP-EDENT median scores: BPS 34.5; CCD 35.8. No clear difference between groups
  1 study · 10 participants
  Very low

14% HP strip vs placebo

• Home‐based chemically‐induced whitening (bleaching) of teeth in adults 2018 · Cochrane All outcomes
  No significant impact of tooth whitening on OHRQoL (Bruhn 2012; Wong 2004)
  2 studies
  GRADE not reported

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

The review found no eligible studies for this question.

• Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
  No quantitative analysis regarding patients' quality of life was possible (no data).
  0 studies
  No studies found

Altered-cast impression technique (ACIP), polyether vs One-piece cast technique (OPC), polyether

The review found no eligible studies for this question.

• Final‐impression techniques and materials for making complete and removable partial dentures 2018 · Cochrane All outcomes
  Not measured
  0 studies
  No studies found

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

The review found no eligible studies for this question.

• Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
  No quantitative analysis regarding patients' quality of life was possible (no data).
  0 studies
  No studies found

Single-stage alginate impression (simplified method) vs Two stage-two step zinc-oxide eugenol (ZoE) traditional method

It is very uncertain whether single-stage alginate impression (simplified method) changes participant-reported oral health-related quality of life (OHIP-EDENT) compared with two stage-two step zinc-oxide eugenol (ZoE) traditional method (very low certainty).

• Final‐impression techniques and materials for making complete and removable partial dentures 2018 · Cochrane All outcomes

  6 months
  MD 0.5 [-2.67, 3.67]
  1 study · 39 participants
  Very low

Alginate (two stage-two step final/wash impression) vs Silicone elastomer (two stage-two step)

Alginate (two stage-two step final/wash impression) may leads to higher participant-reported oral health-related quality of life… compared with silicone elastomer (two stage-two step) (low certainty).

• Final‐impression techniques and materials for making complete and removable partial dentures 2018 · Cochrane All outcomes

  2 weeks
  MD 7.20 [2.71, 11.69]
  1 study · 144 participants
  Low

Autologous platelet concentrates (APC) + open flap debridement (OFD) + bone graft (BG) vs OFD + BG (open flap debridement + bone graft)

The review found no eligible studies for this question.

• Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes
  No quantitative analysis regarding patients' quality of life was possible (no data).
  0 studies
  No studies found

Tranexamic acid vs placebo + standard care

Tranexamic acid probably leads to lower control of epistaxis: episodes of re‐bleeding over 10 days All… compared with placebo plus usual care or usual care alone (moderate certainty).

• Tranexamic acid for patients with nasal haemorrhage (epistaxis) 2018 · Cochrane Headline outcomes only
  RR 0.71 [0.56, 0.9]
  3 studies · 225 participants
  Moderate

Tranexamic acid vs placebo + standard care

Tranexamic acid probably leads to lower control of epistaxis: episodes of re‐bleeding over 10 days Oral… compared with placebo plus usual care or usual care alone (moderate certainty).

• Tranexamic acid for patients with nasal haemorrhage (epistaxis) 2018 · Cochrane Headline outcomes only
  RR 0.73 [0.55, 0.96]
  2 studies · 157 participants
  Moderate

CBT‐combined vs control

• Psychological interventions for needle‐related procedural pain and distress in children and adolescents 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 95 participants
  Very low

CBT‐combined vs control

• Psychological interventions for needle‐related procedural pain and distress in children and adolescents 2018 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 1105 participants
  Low

Hypnosis vs control

• Psychological interventions for needle‐related procedural pain and distress in children and adolescents 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 69 participants
  Very low

Hypnosis vs control

• Psychological interventions for needle‐related procedural pain and distress in children and adolescents 2018 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 193 participants
  Very low