Findings

What do systematic reviews say?

4,410 questions · 8,901 findings · 1,091 reviews

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No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Intervention not reported

Subgroup 1: Length of hospital stay (days) distal to ligament of Treitz · lower gastrointestinal surgery

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 1156 participants
Low

Intervention not reported

Subgroup 2: Length of hospital stay (days) distal and proximal to ligament of Treitz · lower gastrointestinal surgery

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 190 participants
Low

Intervention not reported

Subgroup 3: Length of hospital stay (days) oral feeding only · lower gastrointestinal surgery

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 1075 participants
Low

Intervention not reported

Subgroup 4: Length of hospital stay (days) tube feeding with/without oral feeding · lower gastrointestinal surgery

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 271 participants
Very low

Intervention not reported

Sensitivity analysis 2: Removing studies with imputed results · lower gastrointestinal surgery

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 396 participants
Very low

Intervention not reported

Senstivity analysis 3: Worst case scenario imputation · lower gastrointestinal surgery

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 235 participants
Low

Intervention not reported

Senstivity analysis 4: Best case scenario imputation · lower gastrointestinal surgery

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 235 participants
Low

Half strength formula vs full strength formula

Episodes of abdominal distention > 2 cm · exclusively formula‐fed preterm or low birth weight infants

1 finding from 1 review

Dilute versus full‐strength formula in exclusively formula‐fed preterm or low birth weight infants 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 88 participants
Low

Half strength formula vs full strength formula

Episodes of gastric residuals3 > 50% of last feed remaining · exclusively formula‐fed preterm or low birth weight infants

1 finding from 1 review

Dilute versus full‐strength formula in exclusively formula‐fed preterm or low birth weight infants 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 88 participants
Low

Half strength formula vs full strength formula

Days until 420 joules per kilogram · exclusively formula‐fed preterm or low birth weight infants

1 finding from 1 review

Dilute versus full‐strength formula in exclusively formula‐fed preterm or low birth weight infants 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 88 participants
Low

Half strength formula vs full strength formula

Necrotising enterocolitis · exclusively formula‐fed preterm or low birth weight infants

The review found no eligible studies for this question.

1 finding from 1 review

Dilute versus full‐strength formula in exclusively formula‐fed preterm or low birth weight infants 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Half strength formula vs full strength formula

Mortality before hospital discharge · exclusively formula‐fed preterm or low birth weight infants

The review found no eligible studies for this question.

1 finding from 1 review

Dilute versus full‐strength formula in exclusively formula‐fed preterm or low birth weight infants 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Half strength formula vs full strength formula

Invasive infection (any organism) · exclusively formula‐fed preterm or low birth weight infants

The review found no eligible studies for this question.

1 finding from 1 review

Dilute versus full‐strength formula in exclusively formula‐fed preterm or low birth weight infants 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Outpatient vs inpatients ‐ adults

Treatment failure · Adult patients with cancer who develop a low‐risk febrile neutropaenic event

Outpatients showed no clear difference in treatment failure compared with inpatients ‐ adults (moderate certainty).

1 finding from 1 review

Outpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event 2019 · Cochrane Headline outcomes only
RR 1.23 [0.82, 1.85]
6 studies · 628 participants
Moderate

Outpatient vs inpatients ‐ children

Adverse drug reactions · Children with cancer who develop a low‐risk febrile neutropaenic event

Outpatients showed no clear difference in adverse drug reactions compared with inpatients ‐ children (low certainty).

1 finding from 1 review

Outpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event 2019 · Cochrane Headline outcomes only
RR 1.9 [0.61, 5.98]
2 studies · 156 participants
Low

Outpatient vs inpatients ‐ children

Duration of neutropaenia (days) · Children with cancer who develop a low‐risk febrile neutropaenic event

1 finding from 1 review

Outpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 268 participants
Moderate

Outpatient vs inpatients ‐ children

Length of hospitalisation (days) · Children with cancer who develop a low‐risk febrile neutropaenic event

1 finding from 1 review

Outpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 119 participants
Low

Outpatient vs inpatients ‐ children

Duration of antimicrobial treatment (days) · Children with cancer who develop a low‐risk febrile neutropaenic event

1 finding from 1 review

Outpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 305 participants
Low

Outpatient vs inpatients ‐ adults

All‐cause mortality · Adult patients with cancer who develop a low‐risk febrile neutropaenic event

Outpatients showed no clear difference in mortality compared with inpatients ‐ adults (moderate certainty).

1 finding from 1 review

Outpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event 2019 · Cochrane Headline outcomes only
RR 1.04 [0.29, 3.71]
6 studies · 628 participants
Moderate

Outpatient vs inpatients ‐ adults

Fever clearance time · Adult patients with cancer who develop a low‐risk febrile neutropaenic event

1 finding from 1 review

Outpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 169 participants
Low