Findings

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Bone-borne expansion vs Fixed tooth-borne expansion (Hyrax)

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Bone-borne expansion showed no clear difference in crossbite correction compared with fixed tooth-borne expansion (Hyrax) (low certainty).

1 finding from 1 review

Direct composite resin restoration vs Amalgam restoration

Secondary caries · People with permanent or adult posterior teeth requiring restoration (parallel-group trials involved children aged 6 to 12 years)

Direct composite resin restoration showed no clear difference in secondary caries compared with amalgam restoration; GRADE not reported.

3 findings from 1 review

Intervention not reported

Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years)

Caries prevalence was lowest in Addis Ababa at 34.20% (95% CI 8.42 to 59.97); certainty not graded.

1 finding from 1 review

Lower lip bumper vs No active treatment (control)

Lower incisors to mandible (position, mm) at 9 months · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Lower lip bumper led to higher lower incisors to mandible at 6 months compared with no active treatment (control); GRADE not reported.

1 finding from 1 review

Nickel-titanium archwire vs Stainless steel archwire

Amount of crowding (change in mandibular crowding) at 8 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether nickel-titanium archwire changes amount of crowding (change in mandibular crowding) at 8 weeks compared with stainless steel archwire (very low certainty).

1 finding from 1 review

Cervical pull headgear vs Minor interceptive procedures (control)

Size of the jaws (maxillary and mandibular arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Cervical pull headgear led to higher size of the jaws (maxillary and mandibular arch length) compared with minor interceptive procedures (control); GRADE not reported.

1 finding from 1 review

Lower lip bumper vs No active treatment (control)

Size of the lower jaw (arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Lower lip bumper led to higher size of the lower jaw (mandibular arch length) at 6 months compared with no active treatment (control); GRADE not reported.

1 finding from 1 review

Intervention not reported

Dental caries prevalence · General population in Ethiopia (all ages, age range 6-100 years)

Caries prevalence in the Amhara region was 40.44% (95% CI 24.67 to 56.21); certainty not graded.

1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes changes in vertical height of alveolar ridge (mm) compared with extraction alone (very low certainty).

1 finding from 1 review

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with demineralised bone matrix, single particle size changes changes in vertical height of alveolar ridge (mm) compared with ARP with demineralised bone matrix, multiple particle size (very low certainty).

1 finding from 1 review

Fixed tooth-borne expansion (Hyrax) vs Bonded expander plate (acrylic)

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed tooth-borne Hyrax expander showed no clear difference in molar expansion compared with bonded expander plate (acrylic); GRADE not reported.

1 finding from 1 review

Fixed bonded acrylic splint expander vs no treatment

Molar expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed bonded acrylic splint expander showed no clear difference in molar expansion (maxillary intermolar width) compared with no treatment; GRADE not reported.

1 finding from 1 review

Glass ionomer cement (for bracket bonding) vs Resin adhesive

Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances

There is no clear difference in WSL initiation between glass ionomer cement and resin adhesive for bracket bonding (RR 0.72, not significant); certainty of evidence is very low.

1 finding from 1 review

Nickel-titanium archwire vs Multistranded stainless steel archwire

Harms (pain) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth
1 finding from 1 review
  • Orthodontic treatment for crowded teeth in children 2021 · Cochrane All outcomes
    first days
    No difference in overall pain, but more pain with nickel-titanium at 12 hours and day 1 (morning, afternoon, bedtime) vs multistranded stainless steel (Sandhu 2013). Narrative; no pooled estimate.
    1 study
    GRADE not reported