Harms: non-serious adverse effects (headache, discomfort, loosening of temporary anchorage devices) · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances
Light vibrational forces (LVF) showed no clear difference in harms: non-serious adverse effects (headache, discomfort, loosening… compared with conventional orthodontic appliance treatment (placebo or no adjunct); GRADE not reported.
1 finding from 1 review
Overall treatment time wearing orthodontic appliances · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances
Light vibrational forces (LVF) showed no clear difference in duration of orthodontic treatment compared with conventional orthodontic appliance treatment (placebo or no adjunct) (low certainty).
1 finding from 1 review
Total number of orthodontic appliance adjustment appointments during treatment · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances
Light vibrational forces (LVF) showed no clear difference in total number of orthodontic appliance adjustment appointments during… compared with conventional orthodontic appliance treatment (placebo or no adjunct) (low certainty).
1 finding from 1 review
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
No adverse events were reported. Six trials (673 participants) reported no adverse events from the use of chlorhexidine gel; one study (Rubio-Palau 2015) reported gastrointestinal discomfort (30, 18%), dizziness (10,…
7 studies
GRADE not reported
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Tranexamic acid (AMCA cones) showed no clear difference in presence of dry socket compared with placebo (lactose cones); GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Apernyl (acetylsalicylic acid pellet) showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.
1 finding from 1 review
Adverse events due to periodontal therapy · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes adverse events due to periodontal therapy compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
Adverse events such as transient discolouration, altered taste, allergic reaction, hypersensitivity · People undergoing aerosol-generating procedures (AGPs) in a dental setting
The review found no eligible studies for this question.
1 finding from 1 review
Incidence of infection of dental healthcare providers · People undergoing aerosol-generating procedures (AGPs) in a dental setting
The review found no eligible studies for this question.
1 finding from 1 review
Cardiovascular events · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all cardiovascular events compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
Healing of MRONJ · People with established (manifest) MRONJ
Teriparatide 20 microg daily in addition to standard care showed no clear difference in healing of MRONJ (resolution of lesions) compared with placebo in addition to standard care (low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
P-hydroxybenzoic acid showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine rinse (0.12% and 0.2%, pre- and post-extraction) probably leads to lower presence of dry socket compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Gaseous ozone showed no clear difference in presence of dry socket compared with placebo or control; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Artemisia desertorum spreng (Shahaosan) showed no clear difference in presence of dry socket compared with placebo; GRADE not reported.
1 finding from 1 review
All CVD-related death · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all CVD-related death compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
Duration of treatment (days) · Adults (>18 years) with established dry socket following permanent tooth extraction
Metronidazole (intrasocket) led to lower duration of treatment (days) compared with placebo; GRADE not reported.
1 finding from 1 review
Mortality or serious adverse events requiring hospital admission · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
3 trials reported no adverse events. 1 study reported adverse events (alterations in taste, bad taste, staining) in 24/62 in chlorhexidine group versus 0/40 in placebo group, Peto OR = 8.42 (95% CI 3.31 to 21.39). A…
6 studies
GRADE not reported
Change of microbiota in the patient's mouth · People undergoing aerosol-generating procedures (AGPs) in a dental setting
The review found no eligible studies for this question.
1 finding from 1 review