Question · asked by 1 review
Chlorhexidine rinse (0.12% and 0.2%, pre- and post-extraction) vs placebo or no treatment: Adverse events
- Population
- Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
- Intervention
- Chlorhexidine rinse (0.12% and 0.2%, pre- and post-extraction)
- Comparison
- placebo or no treatment
- Outcome
- Adverse events
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Chlorhexidine rinse (0.12% and 0.2%, pre- and post-extraction) vs Placebo or no treatment Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars) · Follow-up: median 7 days Local interventions for the management of alveolar osteitis (dry socket) (2022) · Cochrane All outcomes | 3 trials reported no adverse events. 1 study reported adverse events (alterations in taste, bad taste, staining) in 24/62 in chlorhexidine group versus 0/40 in placebo group, Peto OR = 8.42 (95% CI 3.31 to 21.39). A… | 6 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes | 2021-09 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.