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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

515 questions in 31 reviews · Fertility Regulation

current versions
No studies 99 · 19.2%Ungraded 11 · 2.1%Very low 70 · 13.6%Low 147 · 28.5%Moderate 153 · 29.7%High 35 · 6.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Pain score 1 hour after IUC insertion (5‐point scale) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
no estimate extracted50 participantsLow
Intervention NR
Pain score 2 hours after IUC insertion (5‐point scale) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
no estimate extracted41 participantsLow
Intervention NR
Pain score during IUC insertion (100 mm VAS) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
SMD 0.27 [0.07, 0.46]4 studies · 400 participantsHigh
Intervention NR
Side effect: cramping (before IUC insertion) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
OR 2.64 [1.46, 4.76]4 studies · 466 participantsHigh
Intervention NR
Moderate to severe pain at IUC insertion (dichotomous) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
OR 0.3 [0.16, 0.55]179 participantsLow
Intervention NR
Satisfaction: experience was slightly or not disagreeable · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
OR 4.34 [2.32, 8.12]179 participantsModerate
Intervention NR
Pain score at IUC insertion (100 mm VAS) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
no estimate extracted73 participantsModerate
Intervention NR
Pain score before leaving clinic (100 mm VAS) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
no estimate extracted73 participantsModerate
Intervention NR
Pain score for highest level before leaving clinic (100 mm VAS) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
MD 7.6 [6.48, 8.72]105 participantsModerate
Intervention NR
Side effect: headache · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
OR 5.68 [1.23, 26.19]255 participantsModerate
Intervention NR
Pain score during IUC insertion (10 cm or 100 mm VAS) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
no estimate extracted3 studies · 409 participantsHigh
Intervention NR
Side effect: abdominal pain · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
OR 3.93 [1.41, 10.97]230 participantsModerate
Intervention NR
Side effect: shivering · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
OR 5.48 [1.41, 21.33]79 participantsModerate
Intervention NR
Satisfaction: would choose treatment again · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
OR 0.3 [0.14, 0.65]255 participantsModerate
Intervention NR
Satisfaction: would recommend treatment to friend · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
OR 0.36 [0.16, 0.81]255 participantsModerate
Intervention NR
Pain score at tenaculum placement (100 mm VAS) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
no estimate extracted50 participantsLow
Intervention NR
Pain score for IUC insertion (10 cm VAS) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
no estimate extracted92 participantsModerate
Intervention NR
Pain score for IUC insertion (within 10 min) (100 mm VAS) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
no estimate extracted209 participantsModerate
Intervention NR
Pain score at 30 min post‐insertion (100 mm VAS) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
no estimate extracted114 participantsModerate
Intervention NR
Pain score during IUC insertion (10‐point VAS) · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
no estimate extracted69 participantsModerate
Intervention NR
Satisfaction: insertion experience was unpleasant · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
OR 0.02 [0.01, 0.09]68 participantsModerate
Intervention NR
Satisfaction: would not want treatment in future · women with IUC being inserted
Interventions for pain with intrauterine device insertion (2015) · Cochrane
OR 0.02 [0, 0.08]68 participantsModerate
Intervention NR
Pregnancy (12 months) · women aged ≤ 25 years with desire for contraception
Hormonal and intrauterine methods for contraception for women aged 25 years and younger (2015) · Cochrane
no estimate extracted193 participantsVery low
Intervention NR
Estimated cumulative failure rate (3 years) · women aged ≤ 25 years with desire for contraception
Hormonal and intrauterine methods for contraception for women aged 25 years and younger (2015) · Cochrane
no estimate extracted1130 participantsLow
Intervention NR
Pregnancy (6 months) · women aged ≤ 25 years with desire for contraception
Hormonal and intrauterine methods for contraception for women aged 25 years and younger (2015) · Cochrane
OR 1 [0.05, 18.57]20 participantsModerate
Intervention NR
Continuation (12 months) · women aged ≤ 25 years with desire for contraception
Hormonal and intrauterine methods for contraception for women aged 25 years and younger (2015) · Cochrane
OR 1.48 [0.76, 2.89]193 participantsVery low
Intervention NR
Continuation (1 month; 6 months) · women aged ≤ 25 years with desire for contraception
Hormonal and intrauterine methods for contraception for women aged 25 years and younger (2015) · Cochrane
OR 2.44 [0.19, 31.53]23 participantsModerate
Intervention NR
Continuation (cycles 1 to 3; cycles 4 to 6) · women aged ≤ 25 years with desire for contraception
Hormonal and intrauterine methods for contraception for women aged 25 years and younger (2015) · Cochrane
OR 1.09 [0.49, 2.42]130 participantsModerate
Intervention NR
Continuation (6 months) · women aged ≤ 25 years with desire for contraception
Hormonal and intrauterine methods for contraception for women aged 25 years and younger (2015) · Cochrane
OR 0.38 [0.05, 2.77]20 participantsModerate
Intervention NR
Discontinuation: other personal reasons (12 months) · women aged ≤ 25 years with desire for contraception
Hormonal and intrauterine methods for contraception for women aged 25 years and younger (2015) · Cochrane
OR 0.27 [0.09, 0.85]193 participantsVery low
Intervention NR
Discontinuation: pain, hormonal, bleeding, spotting, other medical, or planning pregnancy (12 months) · women aged ≤ 25 years with desire for contraception
Hormonal and intrauterine methods for contraception for women aged 25 years and younger (2015) · Cochrane
no estimate extracted193 participantsVery low
Intervention NR
All fractures · women
Steroidal contraceptives and bone fractures in women: evidence from observational studies (2015) · Cochrane
RR 1.2 [1.08, 1.34]1365 participantsModerate
Intervention NR
First fracture · women
Steroidal contraceptives and bone fractures in women: evidence from observational studies (2015) · Cochrane
OR 1.55 [1.03, 2.33]819 participantsHigh
Intervention NR
First fracture: radius or ulna; all sites · women
Steroidal contraceptives and bone fractures in women: evidence from observational studies (2015) · Cochrane
RR 1.5 [1.1, 2.1]17032 participantsHigh
Intervention NR
Fracture, any · women
Steroidal contraceptives and bone fractures in women: evidence from observational studies (2015) · Cochrane
OR 1.5 [1.03, 2.18]258189 participantsModerate
Intervention NR
Fracture · women
Steroidal contraceptives and bone fractures in women: evidence from observational studies (2015) · Cochrane
OR 1.44 [1.01, 2.06]258189 participantsModerate
Intervention NR
First fracture · women
Steroidal contraceptives and bone fractures in women: evidence from observational studies (2015) · Cochrane
OR 1.36 [1.15, 1.6]87627 participantsModerate
Surgical abortion procedures: mid‐level providers vs doctors
Failure/incomplete abortion (RCTs) Provider assessment · Patients requesting abortion procedures
Doctors or mid‐level providers for abortion (2015) · Cochrane
RR 2.97 [0.21, 41.82]2 studies · 2789 participantsLow
Medical abortion procedures: mid‐level providers vs doctors
Complications (observational studies) Verifier assessment · Patients requesting abortion procedures
Doctors or mid‐level providers for abortion (2015) · Cochrane
no estimate extracted1 study · 1164 participantsVery low
Surgical abortion procedures: mid‐level providers vs doctors
Failure/incomplete abortion (observational studies) Provider or supervisor assessment · Patients requesting abortion procedures
Doctors or mid‐level providers for abortion (2015) · Cochrane
RR 2.2 [1.34, 3.6]3 studies · 13715 participantsVery low
Surgical abortion procedures: mid‐level providers vs doctors
Complications (RCTs) Provider assessment · Patients requesting abortion procedures
Doctors or mid‐level providers for abortion (2015) · Cochrane
RR 0.99 [0.17, 5.7]2 studies · 2789 participantsLow
Surgical abortion procedures: mid‐level providers vs doctors
Complications (observational studies) Provider or supervisor assessment · Patients requesting abortion procedures
Doctors or mid‐level providers for abortion (2015) · Cochrane
RR 1.38 [0.7, 2.72]3 studies · 13715 participantsVery low
Surgical abortion procedures: mid‐level providers vs doctors
Total complications (RCTs) Provider assessment · Patients requesting abortion procedures
Doctors or mid‐level providers for abortion (2015) · Cochrane
RR 3.07 [0.16, 59.08]2 studies · 2789 participantsLow
Surgical abortion procedures: mid‐level providers vs doctors
Total complications (observational studies) Provider or supervisor assessment · Patients requesting abortion procedures
Doctors or mid‐level providers for abortion (2015) · Cochrane
RR 1.36 [0.86, 2.14]4 studies · 16173 participantsVery low
Medical abortion procedures: mid‐level providers vs doctors
Failure/incomplete abortion (RCTs) Provider assessment · Patients requesting abortion procedures
Doctors or mid‐level providers for abortion (2015) · Cochrane
RR 0.81 [0.48, 1.36]2 studies · 1892 participantsHigh
Medical abortion procedures: mid‐level providers vs doctors
Failure/incomplete abortion (observational studies) Verifier assessment · Patients requesting abortion procedures
Doctors or mid‐level providers for abortion (2015) · Cochrane
RR 1.09 [0.63, 1.88]1 study · 1164 participantsVery low
Medical abortion procedures: mid‐level providers vs doctors
Complications (RCTs) Provider assessment · Patients requesting abortion procedures
Doctors or mid‐level providers for abortion (2015) · Cochrane
no estimate extracted2 studies · 1892 participantsHigh
Immediate vs delayed insertion (LNG‐IUS or CuT380A IUD) for
Expulsion by 6 months Rate in percentage · patients with
Immediate postabortal insertion of intrauterine devices (2014) · Cochrane
RR 2.9 [1.25, 6.71]3 studies · 878 participantsModerate
TCu 220C vs Copper 7
Discontinuation due to pregnancy (750 days) · patients with Immediate insertion Post abortion
Immediate postabortal insertion of intrauterine devices (2014) · Cochrane
RR 0.44 [0.04, 4.83]2 studies · 2274 participantsModerate
TCu 220C vs Copper 7
Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion
Immediate postabortal insertion of intrauterine devices (2014) · Cochrane
RR 0.46 [0.14, 1.5]2 studies · 2274 participantsModerate