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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

515 questions in 31 reviews · Fertility Regulation

current versions
No studies 99 · 19.2%Ungraded 11 · 2.1%Very low 70 · 13.6%Low 147 · 28.5%Moderate 153 · 29.7%High 35 · 6.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings table ‐ 20 mL 1% lidocaine paracervical block vs sham paracervical block
Pain with dilationa,b · people requesting a surgical abortion at less than 11 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 120 participantsHigh
Summary of findings table ‐ 80 mg lidocaine paracervical block vs normal saline paracervical block
Pain during procedure in women who also received topical cervical lidocaine spraya,b · people requesting a surgical abortion at seven weeks' gestation or less
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 54 participantsModerate
Summary of findings table ‐ 14 mL 1% chloroprocaine paracervical block vs normal saline paracervical block
Pain with dilation ‐ not measured · women requesting a surgical abortion at seven to 12 weeks of gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ 14 mL 1% chloroprocaine paracervical block vs normal saline paracervical block
Pain with aspirationa,b · women requesting a surgical abortion at seven to 12 weeks of gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 79 participantsHigh
Summary of findings table ‐ 14 mL 1% chloroprocaine paracervical block vs normal saline paracervical block
Pain during procedure ‐ not measured · women requesting a surgical abortion at seven to 12 weeks of gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Ultracaine paracervical block vs placebo (normal saline) paracervical block/no paracervical block
Pain with dilation ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Ultracaine paracervical block vs placebo (normal saline) paracervical block/no paracervical block
Pain with aspiration ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Ultracaine paracervical block vs placebo (normal saline) paracervical block/no paracervical block
Pain during procedurea,b · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 43 participantsLow
Summary of findings table ‐ Topical cervical lidocaine spray vs ultracaine paracervical block
Pain with dilation ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Topical cervical lidocaine spray vs ultracaine paracervical block
Pain with aspiration ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Topical cervical lidocaine spray vs ultracaine paracervical block
Pain during procedurea,b · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 48 participantsModerate
Summary of findings table ‐ 20 mL 1% lidocaine paracervical block vs sham paracervical block
Pain with aspirationa,b · people requesting a surgical abortion at less than 11 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 120 participantsHigh
Summary of findings table ‐ Intravenous paracetamol vs ultracaine paracervical block
Pain with dilation ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Intravenous paracetamol vs ultracaine paracervical block
Pain with aspiration ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Intravenous paracetamol vs ultracaine paracervical block
Pain during procedurea,b · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 46 participantsModerate
Summary of findings table ‐ Buffered lidocaine vs plain lidocaine
Pain with dilation (10 mL 2% lidocaine)a,b · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 167 participantsModerate
Summary of findings table ‐ Buffered lidocaine vs plain lidocaine
Pain with dilation (20 mL 1% lidocaine)d,e · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 98 participantsLow
Summary of findings table ‐ Buffered lidocaine vs plain lidocaine
Pain with aspiration (lidocaine)a,b · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted2 studies · 291 participantsModerate
Summary of findings table ‐ Buffered lidocaine vs plain lidocaine
Pain with aspiration (20 mL 1% lidocaine)d,e · people requesting a surgical abortion at 13+6 weeks' gestation or less (Chin 2020 included people experiencing an…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 98 participantsLow
Summary of findings table ‐ 20 mL 1% plain lidocaine vs 20 mL 0.25% bupivacaine
Pain with aspirationa,b · people requesting a surgical abortion in the first trimester
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 143 participantsLow
Summary of findings table ‐ 20 mL 1% plain lidocaine vs 20 mL 0.25% bupivacaine
Pain with dilation ‐ not measured · people requesting a surgical abortion in the first trimester
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ 20 mL 1% plain lidocaine vs 20 mL 0.25% bupivacaine
Pain during procedure ‐ not measured · people requesting a surgical abortion in the first trimester
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ 20 mL 1% lidocaine paracervical block vs sham paracervical block
Pain during procedure ‐ not measured · people requesting a surgical abortion at less than 11 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ 20 mL 1% buffered lidocaine vs 20 mL 0.25% bupivacaine
Pain with dilation ‐ not measured · people requesting a surgical abortion in the first trimester
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ 20 mL 1% buffered lidocaine vs 20 mL 0.25% bupivacaine
Pain with aspirationa,b · people requesting a surgical abortion in the first trimester
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 133 participantsModerate
Summary of findings table ‐ 20 mL 1% buffered lidocaine vs 20 mL 0.25% bupivacaine
Pain during procedure ‐ not measured · people requesting a surgical abortion in the first trimester
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ 20 mL 1% lidocaine vs 20 mL 0.5% lidocaine
Pain with dilation ‐ not measured · people requesting a surgical abortion between seven and 14 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ 20 mL 1% lidocaine vs 20 mL 0.5% lidocaine
Pain with aspirationa,b · people requesting a surgical abortion between seven and 14 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 209 participantsVery low
Summary of findings table ‐ 20 mL 1% lidocaine vs 20 mL 0.5% lidocaine
Pain during procedure ‐ not measured · people requesting a surgical abortion between seven and 14 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Three‐ to five‐minute wait between paracervical block injection and cervical dilation vs no wait between paracervical block injection and cervical dilation
Pain with dilationa,b · people requesting a surgical abortion at less than 11 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted2 studies · 357 participantsModerate
Summary of findings table ‐ Three‐ to five‐minute wait between paracervical block injection and cervical dilation vs no wait between paracervical block injection and cervical dilation
Pain with aspirationa,b · people requesting a surgical abortion at less than 11 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted2 studies · 357 participantsLow
Summary of findings table ‐ Three‐ to five‐minute wait between paracervical block injection and cervical dilation vs no wait between paracervical block injection and cervical dilation
Pain during procedure ‐ not measured · people requesting a surgical abortion at less than 11 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ 10 mL 2% cervical lignocaine gel vs 10 mL cervical KY jelly
Pain with dilationa,b · women requesting a surgical abortion between seven and 12 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 131 participantsLow
Summary of findings table ‐ 20 mL 1% lidocaine paracervical block vs normal saline paracervical block
Pain with dilationa,b · people requesting a surgical abortion at less than 14 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 150 participantsVery low
Summary of findings table ‐ 10 mL 2% cervical lignocaine gel vs 10 mL cervical KY jelly
Pain with aspirationa,b · women requesting a surgical abortion between seven and 12 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 131 participantsModerate
Summary of findings table ‐ 10 mL 2% cervical lignocaine gel vs 10 mL cervical KY jelly
Pain during procedure ‐ not measured · women requesting a surgical abortion between seven and 12 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Two pumps of 10% cervical lidocaine spray and paracervical block vs two pumps of cervical normal saline spray and paracervical block
Pain with dilation ‐ not measured · people requesting a surgical abortion at seven weeks' gestation or less
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Two pumps of 10% cervical lidocaine spray and paracervical block vs two pumps of cervical normal saline spray and paracervical block
Pain with aspiration ‐ not measured · people requesting a surgical abortion at seven weeks' gestation or less
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Two pumps of 10% cervical lidocaine spray and paracervical block vs two pumps of cervical normal saline spray and paracervical block
Pain during procedurea,b · people requesting a surgical abortion at seven weeks' gestation or less
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 54 participantsModerate
Summary of findings table ‐ Two puffs of cervical lidocaine spray vs placebo cervical spray/no spray
Pain with dilation ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Two puffs of cervical lidocaine spray vs placebo cervical spray/no spray
Pain with aspiration ‐ not measured · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Two puffs of cervical lidocaine spray vs placebo cervical spray/no spray
Pain during procedurea,b · people requesting a surgical abortion at 5+0 to 7+0 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 45 participantsLow
Summary of findings table ‐ 3 cm deep paracervical block vs 1.5 cm deep paracervical block
Pain with dilationa,b · people requesting a surgical abortion at less than 12 weeks' gestation (Cetin 1997) and in the first trimester (Wiebe…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted2 studies · 229 participantsVery low
Summary of findings table ‐ 3 cm deep paracervical block vs 1.5 cm deep paracervical block
Pain with aspirationa,b · people requesting a surgical abortion at less than 12 weeks' gestation (Cetin 1997) and in the first trimester (Wiebe…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted2 studies · 229 participantsLow
Summary of findings table ‐ 20 mL 1% lidocaine paracervical block vs normal saline paracervical block
Pain with aspirationa,b · people requesting a surgical abortion at less than 14 weeks' gestation
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 150 participantsLow
Summary of findings table ‐ 3 cm deep paracervical block vs 1.5 cm deep paracervical block
Pain during procedure ‐ not measured · people requesting a surgical abortion at less than 12 weeks' gestation (Cetin 1997) and in the first trimester (Wiebe…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ 2 site (4‐8 o?clock) paracervical block vs 4 site (2‐4‐8‐10 o?clock) paracervical block
Pain with dilationa,b · people requesting a surgical abortion at less than 11 weeks' gestation (Renner 2016) and seven to 12 weeks' gestation…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 163 participantsHigh
Summary of findings table ‐ 2 site (4‐8 o?clock) paracervical block vs 4 site (2‐4‐8‐10 o?clock) paracervical block
Pain with aspiration – normal salined,e · people requesting a surgical abortion at less than 11 weeks' gestation (Renner 2016) and seven to 12 weeks' gestation…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted1 study · 41 participantsModerate
Summary of findings table ‐ 2 site (4‐8 o?clock) paracervical block vs 4 site (2‐4‐8‐10 o?clock) paracervical block
Pain with aspiration – local anaesthetica,b,d,e · people requesting a surgical abortion at less than 11 weeks' gestation (Renner 2016) and seven to 12 weeks' gestation…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extracted2 studies · 201 participantsModerate
Summary of findings table ‐ 2 site (4‐8 o?clock) paracervical block vs 4 site (2‐4‐8‐10 o?clock) paracervical block
Pain during procedure ‐ not measured · people requesting a surgical abortion at less than 11 weeks' gestation (Renner 2016) and seven to 12 weeks' gestation…
Local anaesthesia for pain control in first trimester surgical abortion (2024) · Cochrane
no estimate extractedNRNo studies