Cochrane · systematic review · CD009849

Steroidal contraceptives and bone fractures in women: evidence from observational studies

Lopez, LM, Chen, M, Mullins Long, S, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Fertility RegulationAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 66.7%High 2 · 33.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: women
4 questions
OutcomeEffectEvidenceStatus / GRADE
All fractures
RR 1.2 [1.08, 1.34]1365 participantsModerate
First fracture
OR 1.55 [1.03, 2.33]819 participantsHigh
First fracture: radius or ulna; all sites
RR 1.5 [1.1, 2.1]17032 participantsHigh
Fracture, any
OR 1.5 [1.03, 2.18]258189 participantsModerate

Comparison

Population: women
2 questions
OutcomeEffectEvidenceStatus / GRADE
Fracture
OR 1.44 [1.01, 2.06]258189 participantsModerate
First fracture
OR 1.36 [1.15, 1.6]87627 participantsModerate