Anti‐PD1 monoclonal antibodies vs chemotherapy alone
Anti‐PD1 monoclonal antibodies leads to higher tumour response compared with chemotherapy (high certainty).
- RR 3.42 [2.38, 4.92]1367 participantsHigh
Anti‐PD1 monoclonal antibodies leads to higher tumour response compared with chemotherapy (high certainty).
Protease‐modulating matrix dressing regimen showed no clear difference in TIme to complete healing compared with any other dressing regimen (low certainty).
It is very uncertain whether protease‐modulating matrix dressing regimen changes proportion of participants healed ‐ short term (4‐8 weeks) compared with any other dressing regimen (very low certainty).
Protease‐modulating matrix dressing regimen showed no clear difference in proportion of participants healed ‐ medium term (12 weeks) compared with any other dressing regimen (low certainty).
Protease‐modulating matrix dressing regimen showed no clear difference in proportion of participants healed ‐ long term (over 24 weeks) compared with any other dressing regimen (low certainty).
Protease‐modulating matrix dressing regimen showed no clear difference in proportion of participants with 1 or more adverse events at 2‐12 weeks compared with any other dressing regimen (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Adjunct cognitive behavioural therapy showed no clear difference in adverse event: Leaving the study early compared with adjunct supportive psychotherapy (moderate certainty).
Anti‐epileptic drugs showed no clear difference in early seizure Counts of events compared with other anti‐epileptic drugs (low certainty).
Anti‐epileptic drugs showed no clear difference in late seizure Counts of events compared with other anti‐epileptic drugs (moderate certainty).
Anti‐epileptic drugs showed no clear difference in all‐cause mortality compared with other anti‐epileptic drugs (moderate certainty).
It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes serious neonatal morbidity (Reported in Miller 2014 as 'composite… compared with cervical cerclage alone (very low certainty).