Side effects · People with erosive oral lichen planus
1 finding from 1 review
Table 3 (Side-effects). Lin 2005: TGT - menstrual disturbance (6) and leucopenia (1). Tripterygium glucosides are known to be cytotoxic and unsuitable for individuals of child-bearing age.
1 study · 94 participants
GRADE not reported
Side effects · People with erosive oral lichen planus
1 finding from 1 review
Side effects · People with erosive oral lichen planus
1 finding from 1 review
Investigator‐ or physician‐rated global assessment of disease severity · People with erosive oral lichen planus
Ciclosporin rinse led to lower physician Global Assessment (severity of disease) compared with placebo (vehicle); GRADE not reported.
1 finding from 1 review
MD -1.40 [-1.86, -0.94]
1 study · 8 participants
GRADE not reported
Partial response (>33% improvement) · People with erosive oral lichen planus
Fluocinonide in adhesive base showed no clear difference in partial response (>33% improvement) compared with placebo; GRADE not reported.
1 finding from 1 review
Side effects · People with erosive oral lichen planus
1 finding from 1 review
Participant‐reported pain relief of 50% or greater · People with erosive oral lichen planus
Aloe vera gel led to higher pain (>=50% improvement in symptoms) compared with placebo; GRADE not reported.
1 finding from 1 review
Pain reduction (participant-reported symptoms) · People with erosive oral lichen planus
1 finding from 1 review
Partial response (partial or complete response) · People with erosive oral lichen planus
Topical clobetasol propionate 0.025% showed no clear difference in partial response (partial or complete response) compared with topical clobetasol propionate 0.05%; GRADE not reported.
1 finding from 1 review
Reduction in target/mean lesion size · People with erosive oral lichen planus
Topical tacrolimus 0.1% ointment showed no clear difference in reduction in target/mean lesion size compared with topical clobetasol propionate 0.05% ointment; GRADE not reported.
1 finding from 1 review
Side effects · People with erosive oral lichen planus
1 finding from 1 review
Side effects · People with erosive oral lichen planus
1 finding from 1 review
Pain reduction (VAS 0-100) · People with erosive oral lichen planus
Clobetasol-17-propionate 0.025% lipid-loaded microspheres led to lower pain reduction (VAS 0-100) compared with conventional 0.025% clobetasol lipophilic ointment in hydrophilic…; GRADE not reported.
1 finding from 1 review
Pruritus · children with eczema
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Secondary outcome: clinical flare · adults with eczema
1 finding from 1 review
Pruritus · adults with eczema
1 finding from 1 review
Primary outcome 2. Proportion of participants reporting adverse effects and serious adverse events throughout the study period · adults with eczema
Fexofenadine 120 mg/d showed no clear difference in primary outcome 2. Proportion of participants reporting adverse… compared with placebo (1‐week intervention) (moderate certainty).
1 finding from 1 review
Secondary outcome 1. Mean change in physician‐assessed clinical signs This outcome was assessed as investigator‐assessed change in the ratio of pruritus area to body surface area · adults with eczema
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Moderate
Secondary outcome: quality of life · adults with eczema
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Secondary outcome 3. Number of eczema flares, measured by, for example, ‘escalation of treatment’ or ‘use of topical anti‐inflammatory medications’ Amount of 0.1% hydrocortisone butyrate cream used during the study · adults with eczema
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Moderate