Question · asked by 1 review
Clobetasol-17-propionate 0.025% lipid-loaded microspheres vs Clobetasol propionate 0.025% ointment: Pain reduction (VAS 0-100)
- Population
- People with erosive oral lichen planus
- Intervention
- Clobetasol-17-propionate 0.025% lipid-loaded microspheres
- Comparison
- Clobetasol propionate 0.025% ointment
- Outcome
- Pain reduction (VAS 0-100)
Clobetasol-17-propionate 0.025% lipid-loaded microspheres led to lower pain reduction (VAS 0-100) compared with conventional 0.025% clobetasol lipophilic ointment in hydrophilic…; GRADE not reported.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Clobetasol-17-propionate 0.025% lipid-loaded microspheres vs Conventional 0.025% clobetasol lipophilic ointment in hydrophilic phase Pain reduction (VAS 0-100) · People with erosive oral lichen planus Clobetasol-17-propionate 0.025% lipid-loaded microspheres led to lower pain reduction (VAS 0-100) compared with conventional 0.025% clobetasol lipophilic ointment in hydrophilic…; GRADE not reported. Interventions for erosive lichen planus affecting mucosal sites (2012) · Cochrane All outcomes | MD -18.30 [-28.57, -8.03] | 1 study · 45 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes | 2009-09 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.