Question · asked by 1 review
Tacrolimus 0.1% vs Topical clobetasol propionate 0.05% ointment: Reduction in target/mean lesion size
- Population
- People with erosive oral lichen planus
- Intervention
- Tacrolimus 0.1%
- Comparison
- Topical clobetasol propionate 0.05% ointment
- Outcome
- Reduction in target/mean lesion size
Topical tacrolimus 0.1% ointment showed no clear difference in reduction in target/mean lesion size compared with topical clobetasol propionate 0.05% ointment; GRADE not reported.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Topical tacrolimus 0.1% ointment vs Topical clobetasol propionate 0.05% ointment Reduction in target/mean lesion size · People with erosive oral lichen planus Topical tacrolimus 0.1% ointment showed no clear difference in reduction in target/mean lesion size compared with topical clobetasol propionate 0.05% ointment; GRADE not reported. Interventions for erosive lichen planus affecting mucosal sites (2012) · Cochrane All outcomes | MD 0.00 [-1.09, 1.10] | 1 study · 29 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes | 2009-09 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.