Mental state: No clinically important improvement · patients with schizophrenia
STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) showed no clear difference in mental state: No clinically important improvement ‐ PANSS ‐ when… compared with ANY DOSE ‐ short term (moderate certainty).
4 findings from 1 review
Show 1 more finding
Adverse effects: 6. Movement disorders ‐ specific symptoms ‐ dystonia ‐ versus low dose (greater than or equal to 2‐<4 mg/day) · patients with schizophrenia
STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) probably leads to higher adverse effects: 6. Movement disorders ‐ specific symptoms ‐… compared with ANY DOSE ‐ short term (moderate certainty).
1 finding from 1 review
Adverse effects: 6. Movement disorders ‐ specific symptoms ‐ EPS: unspecified ‐ versus low dose (greater than or equal to 2‐<4 mg/day) · patients with schizophrenia
STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) probably leads to higher adverse effects: 6. Movement disorders ‐ specific symptoms ‐ EPS:… compared with ANY DOSE ‐ short term (moderate certainty).
1 finding from 1 review
Tremor · patients with schizophrenia
STANDARD‐LOWER DOSE (greater than or equal to 4‐<6 mg/day) probably leads to higher adverse effects: 6. Movement disorders ‐ specific symptoms ‐ tremor… compared with ANY DOSE ‐ short term (moderate certainty).
1 finding from 1 review
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
It is very uncertain whether fluoride toothpaste less than 1000 ppm (lower concentration) changes fluorosis (percentage prevalence in permanent teeth) compared with fluoride toothpaste 1000 ppm or more (higher concentration) (very low certainty).
2 findings from 1 review
Periodontitis and allostatic load · US adults in NHANES III
Allostatic load partly explained socioeconomic gradients in periodontal disease.
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Periodontitis and allostatic load · US adults in NHANES 1999-2004
Allostatic load increased the probability of periodontitis and the association varied by race/ethnicity.
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Caries experience (mean DMFT) · Adults aged 19-60 years
Pooled caries experience (DMFT) was similar in very-high-HDI and high-HDI countries, and meta-regression found no significant association between national HDI and DMFT; ungraded observational evidence with very high heterogeneity.
3 findings from 1 review
Caries experience (mean DMFT) · Adults aged 19-60 years
The proportion of university-educated people was not associated with caries experience (DMFT); pooled DMFT was similar across subgroups and the meta-regression was non-significant; ungraded observational evidence.
5 findings from 1 review
Show 2 more findings
Determinants of oral diseases · Adult residents of slums and non-slum urban settings of LMICs
Age, education, income, oral-hygiene behaviour, dental-visit pattern and slum/disadvantaged residence are associated with oral disease; gender effects are disease-specific; ungraded.
1 finding from 1 review
Fourteen studies reported determinants: older age, less education, lower income, poor oral hygiene behaviour (brushing frequency, technique), infrequent dental visits and disadvantaged/slum residential setting were…
14 studies
GRADE not reported
Gastrointestinal bleeding · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with cardiopulmonary bypass
Prophylactic corticosteroids showed no clear difference in gastrointestinal (GI) bleeding (as defined by study authors,… compared with placebo or no corticosteroids (low certainty).
1 finding from 1 review
Adverse effects during treatment ‐ heaviness in lower abdomen · endometrial hyperplasia
It is very uncertain whether summary of findings table ‐ Metformin + levonorgestrel (intrauterine… changes adverse effects during treatment ‐ heaviness in lower abdomen compared with levonorgestrel intrauterine system (very low certainty).
1 finding from 1 review
Depressive symptomatology (lower = less depressive symptomatology): end‐of‐intervention · older people with depression
1 finding from 1 review
Anxious symptomatology (lower = less anxious symptomatology): end‐of‐intervention · older people with depression
1 finding from 1 review
Lower urinary tract symptoms · men with sexual dysfunction
The review found no eligible studies for this question.
2 findings from 1 review
Lower urinary tract symptoms · men with sexual dysfunction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Lower urinary tract symptoms · men with sexual dysfunction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain (PIPP) · neonates with mechanical ventilation
Familiar odour (breast milk smell) showed no clear difference in PIPP during endotracheal suctioning Range of scale 0 to 21. Lower… compared with standard care (low certainty).
1 finding from 1 review
Pain (PIPP) · neonates with mechanical ventilation
White noise showed no clear difference in PIPP during endotracheal suctioning Range of scale 0 to 21 Lower… compared with standard care (low certainty).
1 finding from 1 review
Pain (PIPP) · neonates with mechanical ventilation
Facilitated tucking / four‐handed care / gentle human touch showed no clear difference in PIPP during endotracheal suctioning Range of scale 0 to 21. Lower… compared with standard care (moderate certainty).
1 finding from 1 review