Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

778 questions · 809 findings · 116 reviews

No studies found 205 · 25.3%GRADE not reported 111 · 13.7%Very low 225 · 27.8%Low 155 · 19.2%Moderate 85 · 10.5%High 28 · 3.5%

Face‐down positioning vs other positioning

Proportion of eyes with retinal displacement at 6 months or later (RR < 1 favored) · people with primary macula‐involving rhegmatogenous retinal detachments

It is very uncertain whether face‐down positioning changes proportion of eyes with retinal displacement at 6 months or later… compared with other positioning (very low certainty).

1 finding from 1 review

Face‐down positioning vs other positioning

Visual acuity · people with primary macula‐involving rhegmatogenous retinal detachments

It is very uncertain whether face‐down positioning changes mean change in logMAR or Snellen visual acuity from baseline to 3… compared with other positioning (very low certainty).

1 finding from 1 review

Face‐down positioning vs other positioning

Mean objective distortion score at 3 months or later (lower is favored) · people with primary macula‐involving rhegmatogenous retinal detachments

It is very uncertain whether face‐down positioning changes mean objective distortion score at 3 months or later (lower is… compared with other positioning (very low certainty).

1 finding from 1 review

Face‐down positioning vs other positioning

Quality of life assessments at 3 months or later (higher is favored) · people with primary macula‐involving rhegmatogenous retinal detachments

It is very uncertain whether face‐down positioning changes quality of life assessments at 3 months or later (higher is favored) compared with other positioning (very low certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Long‐term ipsilateral stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher ipsilateral stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Intervention not reported

Pain intensity measured on CHQ (0‐100; 0 = worse pain), and VAS (0 to 100; 0 = no pain) Postintervention: first assessment after end of treatment; no later than 3 months · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain
1 finding from 1 review

Intervention not reported

Quality of life measured on multiple scales (0 to 100; higher score = better quality of life) Postintervention: first assessment after end of treatment; no later than 3 months · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain
1 finding from 1 review

Responsive complementary feeding (RCF) / other caregivers' feeding practices vs Other models of complementary feeding (traditional/non-responsive CF)

Type 2 diabetes (later in life) · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries

No eligible studies examined the influence of complementary feeding practices on later type 2 diabetes; this is an evidence gap.

1 finding from 1 review

Responsive complementary feeding (RCF) / other caregivers' feeding practices vs Other models of complementary feeding (traditional/non-responsive CF)

Hypertension (later in life) · Healthy, term-born, normal-birth-weight infants aged 4-24 months (breastfed and/or formula-fed) in Western industrialized countries

No eligible studies examined the influence of complementary feeding practices on later hypertension; this is an evidence gap.

1 finding from 1 review

Main comparison of patch angioplasty vs primary closure

Stroke · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…

It is very uncertain whether main comparison of patch angioplasty changes any stroke (fatal or non‐fatal; contralateral, ipsilateral or… compared with primary closure (very low certainty).

1 finding from 1 review

Main comparison of patch angioplasty vs primary closure

Perioperative ipsilateral stroke (< 30 days) · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…

It is very uncertain whether main comparison of patch angioplasty changes ipsilateral stroke (fatal or non‐fatal; haemorrhage or infarct)… compared with primary closure (very low certainty).

1 finding from 1 review

Main comparison of patch angioplasty vs primary closure

Long‐term any stroke · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…

It is very uncertain whether main comparison of patch angioplasty changes any stroke (fatal or non‐fatal; contralateral, ipsilateral or… compared with primary closure (very low certainty).

1 finding from 1 review

Main comparison of patch angioplasty vs primary closure

Long‐term ipsilateral stroke · patients undergoing carotid endarterectomy, whether the initial indication for endarterectomy was symptomatic or asymptomatic carotid…

It is very uncertain whether main comparison of patch angioplasty changes ipsilateral stroke (fatal or non‐fatal; haemorrhage or infarct)… compared with primary closure (very low certainty).

1 finding from 1 review