All‐cause mortality, neonates, IgM‐enriched polyclonal IVIG · neonates with sepsis, severe sepsis and septic shock
Polyclonal intravenous immunoglobulin (IVIG) showed no clear difference in all‐cause mortality, neonates, IgM‐enriched polyclonal IVIG compared with placebo or no intervention (low certainty).
1 finding from 1 review
28‐Day all cause mortality (adult studies) · adult patients with sepsis, severe sepsis and septic shock
Polyclonal intravenous immunoglobulin (IVIG) probably leads to lower all‐cause mortality, adults, standard polyclonal IVIG compared with placebo or no intervention (moderate certainty).
5 findings from 1 review
RR 0.81 [0.7, 0.93]
10 studies · 1430 participants
Moderate
RR 0.66 [0.51, 0.85]
7 studies · 528 participants
Moderate
RR 0.97 [0.81, 1.15]
5 studies · 945 participants
High
Show 2 more findings
All‐cause mortality(7‐day) · people with intermediate‐risk (submassive) APE
1 finding from 1 review
All‐cause mortality (90‐day) · people with intermediate‐risk (submassive) APE
It is very uncertain whether ultrasound‐assisted catheter‐directed thrombolysis plus standard… changes all‐cause mortality (90‐day) compared with standard intravenous heparinisation (very low certainty).
1 finding from 1 review
Treatment‐associated major haemorrhage ( · people with intermediate‐risk (submassive) APE
1 finding from 1 review
Treatment‐associated minor haemorrhage ( · people with intermediate‐risk (submassive) APE
It is very uncertain whether ultrasound‐assisted catheter‐directed thrombolysis plus standard… changes treatment‐associated minor haemorrhage ( compared with standard intravenous heparinisation (very low certainty).
1 finding from 1 review
Recurrent APE requiring retreatment or change to a different APE treatment ( · people with intermediate‐risk (submassive) APE
1 finding from 1 review
Length of hospital stay · people with intermediate‐risk (submassive) APE
1 finding from 1 review
Quality of life  · people with intermediate‐risk (submassive) APE
1 finding from 1 review
Oral mucositis (severe) · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies
Glutamine (intravenous) led to lower oral mucositis (severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Caesarean section · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…
Discontinued intravenous (IV) oxytocin stimulation may leads to lower caesarean delivery compared with continued IV oxytocin stimulation (low certainty).
1 finding from 1 review
Caesarean delivery after active phase has begun, using "reached active phase" as the denominator · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…
Discontinued intravenous (IV) oxytocin stimulation showed no clear difference in caesarean delivery after active phase has begun, using "reached… compared with continued IV oxytocin stimulation (moderate certainty).
1 finding from 1 review
Uterine tachysystole combined with abnormal fetal heart rate · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…
Discontinued intravenous (IV) oxytocin stimulation probably leads to lower uterine tachysystole combined with abnormal fetal heart rate compared with continued IV oxytocin stimulation (moderate certainty).
1 finding from 1 review
Chorioamnionitis · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…
It is very uncertain whether discontinued intravenous (IV) oxytocin stimulation changes chorioamnionitis compared with continued IV oxytocin stimulation (very low certainty).
1 finding from 1 review
Use of analgesia and epidural during labour · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…
Discontinued intravenous (IV) oxytocin stimulation may leads to higher use of analgesia and epidural during labour compared with continued IV oxytocin stimulation (low certainty).
1 finding from 1 review
Intrapartum cardiotocography (CTG) abnormalities (suspicious/pathological CTGs) · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…
Discontinued intravenous (IV) oxytocin stimulation probably leads to lower intrapartum cardiotocography (CTG) abnormalities… compared with continued IV oxytocin stimulation (moderate certainty).
1 finding from 1 review
Apgar score less than 7 at 5 minutes · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…
Discontinued intravenous (IV) oxytocin stimulation may leads to lower apgar score at five minutes below seven compared with continued IV oxytocin stimulation (low certainty).
1 finding from 1 review
Acidotic cord gasses (arterial umbilical pH < 7.10) · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…
Discontinued intravenous (IV) oxytocin stimulation may leads to higher acidotic cord gasses (arterial umbilical pH < 7.10) compared with continued IV oxytocin stimulation (low certainty).
1 finding from 1 review
Number of responders · IBD patients
Intravenous preparations may leads to higher number of responders compared with oral preparations (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · IBD patients
Intravenous preparations may leads to lower withdrawal due to adverse events compared with oral preparations (low certainty).
1 finding from 1 review