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Evidence found and GRADE certainty

319 questions · 323 findings · 28 reviews · Eyes and Vision

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No studies found 85 · 26.3%GRADE not reported 10 · 3.1%Very low 80 · 24.8%Low 103 · 31.9%Moderate 41 · 12.7%High 4 · 1.2%

Lateral rectus recession and medial rectus plication vs lateral rectus recession and medial rectus resection

Stereoacuity at distance Loss of ≥ 2 octaves near stereoacuity Measured using the Preschool Randot test 3 years after surgery · people with intermittent exotropia, aged over 6 years

The review found no eligible studies for this question.

1 finding from 1 review

Lateral rectus recession and medial rectus plication vs lateral rectus recession and medial rectus resection

Motor alignment at distance fixation Measured using the PACT at 1 year · people with intermittent exotropia, aged over 6 years

Lateral rectus recession and medial rectus plication showed no clear difference in motor alignment at distance fixation Measured using the PACT at 1 year compared with lateral rectus recession and medial rectus resection (low certainty).

1 finding from 1 review

Lateral rectus recession and medial rectus plication vs lateral rectus recession and medial rectus resection

Motor fusion test · people with intermittent exotropia, aged over 6 years

It is very uncertain whether lateral rectus recession and medial rectus plication changes motor fusion test Measured using the synoptophore and Titmus fly… compared with lateral rectus recession and medial rectus resection (very low certainty).

1 finding from 1 review

Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Motor alignment at distance Change in exotropia control at near fixation, measured from baseline to 3 years using the prism and alternate cover test · people with intermittent exotropia, aged 3 to < 11 years

Bilateral lateral rectus recession showed no clear difference in motor alignment at distance Change in exotropia control at near… compared with unilateral lateral rectus recession with medial rectus resection (moderate certainty).

1 finding from 1 review

Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Minor adverse events Defined as any adverse event within 8 weeks of surgery that does not require further intervention · people with intermittent exotropia, aged 3 to < 11 years

Bilateral lateral rectus recession showed no clear difference in minor adverse events Defined as any adverse event within 8 weeks of… compared with unilateral lateral rectus recession with medial rectus resection (low certainty).

1 finding from 1 review

Patching vs active observation

Motor alignment at near fixation Measured using PACT at 6 months · people with intermittent exotropia, aged less than 11 years

Patching showed no clear difference in motor alignment at near fixation Measured using PACT at 6 months compared with active observation (high certainty).

1 finding from 1 review

Patching vs active observation

Stereoacuity at near · people with intermittent exotropia, aged less than 11 years

Patching showed no clear difference in stereoacuity at near Measured using the Preschool Randot, Titmus… compared with active observation (low certainty).

1 finding from 1 review

Topical mydriatics vs intracameral mydriatics

AE: cystoid macular edema · patients undergoing cataract surgery

Topical mydriatics showed no clear difference in AE: cystoid macular edema compared with intracameral mydriatics (low certainty).

2 findings from 1 review