Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

426 questions · 433 findings · 18 reviews · Implants and prosthodontics

No studies found 45 · 10.4%GRADE not reported 341 · 78.8%Very low 36 · 8.3%Low 6 · 1.4%Moderate 5 · 1.2%High 0 · 0%

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Prosthesis failure · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in prosthesis failure compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Postoperative infection · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in postoperative infection compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review

Zygomatic implants without bone grafts (as a complete alternative to any bone augmentation procedure) vs Conventional dental implants in augmented maxillae

Implant failure rate · Participants with an atrophic maxilla who cannot be rehabilitated with conventional dental implants due to lack of bone (including…

The review found no eligible studies for this question.

1 finding from 1 review

Zygomatic implants for retaining a maxillary obturator vs Non-implant retained obturators, local and regional flaps, or microvascular free flaps

Outcome not reported · Patients requiring maxillary reconstruction after partial or total maxillectomy (cancer patients)

The review found no eligible studies for this question.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Cost‐effectiveness · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

The review found no eligible studies for this question.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Implant failure · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in implant failure compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Postimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in postimplantation complications compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Implant failure · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) probably leads to lower implant failure compared with no antibiotics or placebo (moderate certainty).

1 finding from 1 review

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Adverse events · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in adverse events compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review

Implant surface smoothening added to systemic antibiotics + resective surgery + local antibiotics vs No implant surface smoothening (same surgical protocol)

Implant failure · People with at least one dental implant affected by perimplantitis

Implant surface smoothening added to systemic antibiotics +… showed no clear difference in implant failure compared with no implant surface smoothening (same surgical protocol); GRADE not reported.

1 finding from 1 review

Low-gold (Midas) or silver-palladium (Albacast) alloy FDP vs High-gold content control alloy (JS C) FDP

Visual marginal discrepancy (3 years) · Patients receiving single crowns and FDPs; split-mouth

Low-gold (Midas) or silver-palladium (Albacast) alloy FDP showed no clear difference in visual marginal discrepancy (3 years) compared with high-gold content control alloy (JS C) FDP; GRADE not reported.

1 finding from 1 review

Fixed dental prosthesis (cantilever FDP) vs Removable dental prosthesis (RDP)

Incidence-free survival (caries, endodontic treatment, tooth loss) · Patients with a shortened dental arch (missing posterior teeth)

Fixed dental prosthesis (cantilever FDP) showed no clear difference in incidence-free survival (caries, endodontic treatment, tooth loss) compared with removable dental prosthesis (RDP); GRADE not reported.

1 finding from 1 review

Er:YAG laser surface debridement before bone augmentation vs Plastic curettes plus saline solution before bone augmentation

Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis

Er:YAG laser surface debridement before bone augmentation showed no clear difference in change in probing attachment level (PAL gain) compared with plastic curettes plus saline solution before bone augmentation; GRADE not reported.

1 finding from 1 review