Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

606 questions · 682 findings · 77 reviews

No studies found 99 · 14.5%GRADE not reported 215 · 31.5%Very low 197 · 28.9%Low 102 · 15%Moderate 48 · 7%High 21 · 3.1%

Intervention not reported

Re‐exposure to IPV score Scales: Revised Conflict Tactics Scales, Composite Abuse Scale Direction: lower better · women aged 16 years and older who self‐report previous or current experience of intimate partner violence
1 finding from 1 review

Biomedical risk assessment vs Control (waitlist, routine/standard oral health education, or minimal intervention)

Smoking cessation · people who smoke

Biomedical risk assessment showed no clear difference in feedback on smoking exposure Smoking cessation at longest compared with standard care or minimal intervention (moderate certainty).

1 finding from 1 review

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Exposure of the plate (adverse effect) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
  • Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomes
    Up to 3 years postoperatively
    Both titanium and resorbable groups experienced two plate exposures which occurred between the third and ninth month, with plate exposure rates of 1.02% for the titanium group and 1.21% for the resorbable group. All…
    1 study · 60 participants
    GRADE not reported

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Adverse effects (composite: plate exposure, wound infection, sinus tract, wound dehiscence, plate removal) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
  • Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomes
    Up to 24 months postoperatively
    SoF row. Adverse effects; 60 participants (1 RCT); Quality of the evidence (GRADE): VERY LOW. Exposure of the plate: both titanium and resorbable groups experienced 2 plate exposures which occurred between the third…
    1 study · 60 participants
    Very low

Anterior prolapse repair: native tissue vs polypropylene mesh

Repeat surgery ‐ surgery for prolapse, SUI, or mesh exposure review 1 to 3 years · women with anterior compartment pelvic organ prolapse

Anterior prolapse repair: native tissue probably leads to lower repeat surgery for prolapse, SUI or mesh exposure (1‐3 years) compared with polypropylene mesh (moderate certainty).

1 finding from 1 review

Intervention not reported

Proportion of successful procedures at 1 year and up to 5 years after surgery (no exposure/extrusion) · people with anophthalmic sockets

The intervention showed no clear difference in proportion of successful procedures at 1 year and up to 5 years… (low certainty).

1 finding from 1 review

Intervention not reported

Co‐operation during induction ‐ Mask introduction/exposure (Mask) ICC (number of children compliant) · children

It is very uncertain whether the intervention changes co‐operation during induction ‐ Mask introduction/exposure (Mask)… (very low certainty).

1 finding from 1 review

Partial caries removal (single stage; residual dentinal caries sealed into the tooth definitively) vs Complete caries removal

Pulp exposure during caries removal · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

Partial caries removal (single stage; residual dentinal caries… probably leads to lower pulp exposure during caries removal compared with complete caries removal (moderate certainty).

1 finding from 1 review

Stepwise excavation (two-stage caries removal, re-entry after an interval) vs Complete caries removal

Pulp exposure during caries removal · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

Stepwise excavation (two-stage caries removal, re-entry after an… probably leads to lower pulp exposure during caries removal compared with one stage complete caries removal (moderate certainty).

3 findings from 1 review

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Adverse effects (insufficient fixation; re-operation/revision; plate exposure; superficial or deep wound infection; sinus tract; wound dehiscence; giant cell/foreign body or inflammatory reaction; post-traumatic dystrophy) · Adults over 18 years of age with fractures of the facial skeleton including the mandible, maxilla, zygoma (malar); studies on fractures of…

The review found no eligible studies for this question.

1 finding from 1 review
  • Resorbable versus titanium plates for facial fractures 2009 · Cochrane All outcomes
    Up to 3 years postoperatively
    Planned adverse-effects outcome not assessed: none of the retrieved studies met the inclusion criteria, so no data were available for analysis. Verbatim (Effects of interventions): "Although 53 studies were retrieved…
    0 studies
    No studies found

Mineral trioxide aggregate (MTA) vs Calcium hydroxide (CH)

Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure

In partial pulpotomy, MTA had significantly higher success than calcium hydroxide (OR 2.81; ungraded).

5 findings from 2 reviews · compare the 2 reviews
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Full pulpotomy vs Partial pulpotomy

Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure

The three-study meta-analysis found no significant difference between full and partial pulpotomy after 1 year.

1 finding from 1 review

Higher drinking-water fluoride exposure vs Null / lowest drinking-water fluoride exposure (reference)

Spine bone mineral density · Females (all ages)

Among females in low-to-moderate-risk-of-bias studies, the reported spine-BMD estimate above 2.35 mg/L water fluoride was MD 0.07 g/cm2 (95% CI 0.11 to 0.24; ungraded).

2 findings from 1 review

Partial pulpotomy with permanent restoration after 7-14 days vs No comparator

Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure

Permanent restoration after 7-14 days was associated with a pooled success rate of 73.6%.

1 finding from 1 review

Partial pulpotomy with tri-calcium silicate material (MTA or Biodentine) vs No comparator

Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure

Partial pulpotomy with MTA or Biodentine had a pooled success rate of 86.8%.

1 finding from 1 review

Partial pulpotomy with one additional day before permanent restoration vs Partial pulpotomy with one fewer day before permanent restoration

Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure

Each additional day before permanent restoration was associated with a 0.088% decrease in success in meta-regression.

1 finding from 1 review

Partial pulpotomy with permanent restoration after more than 14 days vs No comparator

Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure

Permanent restoration after more than 14 days was associated with a pooled success rate of 23.2%.

1 finding from 1 review

Partial pulpotomy with sodium hypochlorite (NaOCl) hemostatic agent vs Partial pulpotomy without NaOCl / alternative hemostatic agent

Overall success (composite of clinical and radiographic success) · Adults (>=18 y) with mature permanent teeth and deep carious pulp exposure

Using NaOCl during partial pulpotomy is associated with borderline-higher success, independent of concentration (ungraded, exploratory).

1 finding from 1 review