Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

332 questions · 335 findings · 55 reviews · Headline outcomes only

No studies found 77 · 23%GRADE not reported 3 · 0.9%Very low 113 · 33.7%Low 75 · 22.4%Moderate 61 · 18.2%High 6 · 1.8%

Intervention not reported

Endoscopic drainage versus EUS‐guided drainage · patients with pancreatic pseudocysts

It is very uncertain whether the intervention changes endoscopic drainage versus EUS‐guided drainage (very low certainty).

1 finding from 1 review

Budesonide vs mesalamine

Remission (combined clinical and endoscopic remission) · Adult patients with active ulcerative colitis

Budesonide showed no clear difference in remission (combined clinical and endoscopic remission) compared with mesalamine (low certainty).

1 finding from 1 review

Etrolizumab vs placebo

Failure to induce endoscopic remission · patients with induction of remission in ulcerative colitis

Etrolizumab showed no clear difference in failure to enter endoscopic remission at week 6 compared with placebo (moderate certainty).

2 findings from 1 review

Intervention not reported

Endoscopic appearances 0 to 3 (0 = no polyps, 3 = severe polyposis)

The intervention showed no clear difference in endoscopic appearances 0 to 3 (0 = no polyps, 3 = severe polyposis) (low certainty).

1 finding from 1 review