Cochrane · systematic review · CD006774
Unfractionated or low‐molecular weight heparin for induction of remission in ulcerative colitis
Chande, N, Wang, Y, McDonald, JWD, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
LMWH compared to Placebo for induction of remission in ulcerative colitis
Population: patients with induction of remission in ulcerative colitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Endoscopic remission LMWH vs Placebo | RR 1.34 [0.66, 2.72] | 1 study · 141 participants | Very low Downgraded: imprecision |
LMWH + standard therapy compared to Standard therapy for induction of remission in ulcerative colitis
Population: patients with induction of remission in ulcerative colitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Clinical remission LMWH + standard therapy vs Standard therapy | RR 0.8 [0.32, 2.04] | 1 study · 34 participants | Very low Downgraded: risk of bias, imprecision |
Clinical improvement LMWH + standard therapy vs Standard therapy | RR 1.13 [0.83, 1.53] | 1 study · 34 participants | Very low Downgraded: risk of bias, imprecision |
Endoscopic remission LMWH + standard therapy vs Standard therapy | RR 0.8 [0.32, 2.04] | 1 study · 34 participants | Very low Downgraded: risk of bias, imprecision |
Endoscopic improvement LMWH + standard therapy vs Standard therapy | RR 1.13 [0.69, 1.85] | 1 study · 34 participants | Very low Downgraded: risk of bias, imprecision |
UFH compared to Corticosteroids for induction of remission in ulcerative colitis
Population: patients with induction of remission in ulcerative colitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Clinical improvement UFH vs Corticosteroids | RR 0.06 [0, 0.88] | 1 study · 25 participants | Very low Downgraded: risk of bias, imprecision |