Findings

What do systematic reviews say?

509 questions · 521 findings · 45 reviews

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No studies found 87 · 16.7%GRADE not reported 61 · 11.7%Very low 166 · 31.9%Low 120 · 23%Moderate 73 · 14%High 14 · 2.7%

Atypical (standard‐dose) vs atypical (low‐dose) antipsychotics (only short term)

Symptomatic hyperprolactinaemia · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 257 participants
High

Atypical (standard‐dose) vs atypical (low‐dose) antipsychotics (only short term)

Use of antiparkinsonian medications · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 257 participants
High

Atypical (standard‐dose) vs atypical (low‐dose) antipsychotics (only short term)

Weight gain · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 257 participants
High

Atypical vs typical antipsychotics (only short term)

Worse or no improvement · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Low

Atypical vs typical antipsychotics (only short term)

Adverse effects ‐ anticholinergic effects · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Moderate

Atypical vs typical antipsychotics (only short term)

Drop in the absolute neutrophil count below 1500 per mm3 · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Very low

Atypical vs typical antipsychotics (only short term)

Adverse effects: Leaving the study early · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Moderate

Atypical vs atypical antipsychotics (only short term)

No improvement (risperidone vs olanzapine) · people with psychosis

1 finding from 1 review

Atypical antipsychotics for psychosis in adolescents 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 111 participants
Moderate

Benzodiazepines (lorazepam) vs chlorpromazine

Mortality from all causes · adult AIDS patients with delirium

It is very uncertain whether benzodiazepines (lorazepam) changes mortality from all causes compared with antipsychotics (chlorpromazine) (very low certainty).

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
RR 0.87 [0.23, 3.26]
1 study · 19 participants
Very low

Benzodiazepines (lorazepam) vs haloperidol

Length of delirium episode · adult AIDS patients with delirium

The review found no eligible studies for this question.

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Benzodiazepines (lorazepam) vs haloperidol

Severity of delirium · adult AIDS patients with delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Benzodiazepines (lorazepam) vs haloperidol

Any adverse event ESRS, higher = worse · adult AIDS patients with delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Benzodiazepines (lorazepam) vs haloperidol

Duration of hospital admission (days) · adult AIDS patients with delirium

The review found no eligible studies for this question.

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Benzodiazepines (lorazepam) vs haloperidol

Mortality from all causes · adult AIDS patients with delirium

It is very uncertain whether benzodiazepines (lorazepam) changes mortality from all causes compared with antipsychotics (haloperidol) (very low certainty).

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
RR 1.83 [0.34, 9.92]
1 study · 17 participants
Very low

Benzodiazepines (lorazepam) vs chlorpromazine

Length of delirium episode · adult AIDS patients with delirium

The review found no eligible studies for this question.

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Benzodiazepines (lorazepam) vs chlorpromazine

Severity of delirium · adult AIDS patients with delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

Benzodiazepines (lorazepam) vs chlorpromazine

Any adverse event ESRS, higher = worse · adult AIDS patients with delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

Benzodiazepines (lorazepam) vs chlorpromazine

Duration of hospital admission (days) · adult AIDS patients with delirium

The review found no eligible studies for this question.

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

ECT plus standard care vs antipsychotics plus standard care

Satisfaction with treatment: leaving the study early Endpoint data (events) · people with treatment‐resistant schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Electroconvulsive therapy for treatment‐resistant schizophrenia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

ECT plus standard care vs antipsychotics plus standard care

Mental state · people with treatment‐resistant schizophrenia

1 finding from 1 review

Electroconvulsive therapy for treatment‐resistant schizophrenia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 162 participants
Very low