Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

11 questions · 11 findings · 6 reviews · Headline outcomes only

No studies found 3 · 27.3%GRADE not reported 0 · 0%Very low 6 · 54.5%Low 2 · 18.2%Moderate 0 · 0%High 0 · 0%

Evening vs morning dosing regimen

Withdrawals due to adverse events · adults with primary (essential) hypertension whose systolic or diastolic (or both) blood pressure levels were 130/80 mmHg or greater

It is very uncertain whether evening changes withdrawals from treatment due to adverse events compared with morning dosing regimen (very low certainty).

1 finding from 1 review