Findings

What do systematic reviews say?

6 questions · 6 findings · 3 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 66.7%Moderate 2 · 33.3%High 0 · 0%

Withdrawals due to adverse events

Beta‐blockers showed no clear difference in withdrawal due to adverse effect compared with diuretics (low certainty).

1 finding from 1 review

Beta‐blockers for hypertension 2017 · Cochrane Headline outcomes only
RR 1.69 [0.95, 3]
3 studies · 11566 participants
Low

Withdrawals due to adverse events

Beta‐blockers showed no clear difference in withdrawal due to adverse effect compared with calcium‐channel blockers (low certainty).

1 finding from 1 review

Beta‐blockers for hypertension 2017 · Cochrane Headline outcomes only
RR 1.2 [0.71, 2.04]
2 studies · 21591 participants
Low

Withdrawals due to adverse events

Beta‐blockers probably leads to higher withdrawal due to adverse effect compared with renin‐angiotensin system inhibitors (moderate certainty).

1 finding from 1 review

Beta‐blockers for hypertension 2017 · Cochrane Headline outcomes only
RR 1.41 [1.29, 1.54]
2 studies · 9951 participants
Moderate

Withdrawals due to adverse events

Beta‐blockers showed no clear difference in withdrawal due to adverse effect compared with placebo (low certainty).

1 finding from 1 review

Beta‐blockers for hypertension 2017 · Cochrane Headline outcomes only
RR 3.38 [0.82, 13.95]
3 studies · 22729 participants
Low

Withdrawals due to adverse events · adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of nonselective beta‐blockers for primary hypertension 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 729 participants
Low

Adverse effects (side effects; treatment withdrawals) · patients with hypertension

1 finding from 1 review

First‐line diuretics versus other classes of antihypertensive drugs for hypertension 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 18501 participants
Moderate