Adalimumab every other week vs placebo
Adalimumab every other week showed no clear difference in frequency of treatment discontinuation compared with placebo (high certainty).
- RR 4.91 [0.24, 99.74]2 studies · 124 participantsHigh
Adalimumab every other week showed no clear difference in frequency of treatment discontinuation compared with placebo (high certainty).
Adalimumab weekly showed no clear difference in frequency of treatment discontinuation compared with placebo (moderate certainty).
It is very uncertain whether FAE changes AEs leading to treatment discontinuation compared with MTX (very low certainty).
It is very uncertain whether FAE changes common nuisance AEs (not leading to treatment discontinuation) compared with MTX (very low certainty).
FAE probably leads to higher common nuisance AEs (not leading to treatment discontinuation) compared with placebo (moderate certainty).
Imiquimod 5% cream with tazarotene 0.1% gel showed no clear difference in secondary outcome: Discontinuation of treatment because of harms… compared with imiquimod 5% cream alone (low certainty).