Cochrane · systematic review · CD004414
Interventions for preventing occupational irritant hand dermatitis
Bauer, A, Rönsch, H, Elsner, P, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
SkinAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 12.5%Low 3 · 37.5%Moderate 4 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Barrier creams compared to no treatment for preventing occupational irritant hand dermatitis
Population: workers at risk of occupational irritant hand dermatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
The proportion of participants developing any signs and symptoms of OIHD (incident cases) measured by clinical scores (IGA) or hand dermatitis scores (e.g. HECSI, Manuscore), or both, as rated by the investigator (physician/nurse) or the participa... Barrier creams vs no treatment | RR 0.87 [0.72, 1.06] | 4 studies · 999 participants | Low Downgraded: imprecision, inconsistency |
Frequency of treatment discontinuation due to adverse effects Barrier creams vs no treatment | no estimate extracted | 3 studies · 111 participants | Moderate Downgraded: imprecision, inconsistency, indirectness |
Moisturisers compared to no treatment for preventing occupational irritant hand dermatitis
Population: workers at risk of occupational irritant hand dermatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
The proportion of participants developing any signs and symptoms of OIHD (incident cases) measured by clinical scores (IGA) or hand dermatitis scores (e.g. HECSI, Manuscore), or both, as rated by the investigator (physician/nurse) or the participa... Moisturisers vs no treatment | RR 0.71 [0.46, 1.09] | 3 studies · 507 participants | Low Downgraded: imprecision, inconsistency |
Frequency of treatment discontinuation due to adverse effects Moisturisers vs no treatment | no estimate extracted | 2 studies · 133 participants | Moderate Downgraded: imprecision, inconsistency, indirectness |
Barrier creams and moisturisers compared to no treatment for preventing occupational irritant hand dermatitis
Population: workers at risk of occupational irritant hand dermatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
The proportion of participants developing any signs and symptoms of OIHD (incident cases) measured by clinical scores (IGA) or hand dermatitis scores (e.g. HECSI, Manuscore), or both, as rated by the investigator (physician/nurse) or the participa... Barrier creams and moisturisers vs no treatment | RR 0.68 [0.33, 1.42] | 2 studies · 474 participants | Low Downgraded: imprecision, inconsistency |
Frequency of treatment discontinuation due to adverse effects Barrier creams and moisturisers vs no treatment | no estimate extracted | 1 study · 100 participants | Moderate Downgraded: imprecision, inconsistency, indirectness |
Skin protection education compared to no or minimal intervention for preventing occupational irritant hand dermatitis
Population: workers at risk of occupational irritant hand dermatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
The proportion of participants developing any signs and symptoms of OIHD (incident cases) measured by clinical scores (IGA) or hand dermatitis scores (e.g. HECSI, Manuscore), or both, as rated by the investigator (physician/nurse) or the participa... Skin protection education vs no or minimal intervention | RR 0.76 [0.54, 1.08] | 3 studies · 13551 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Frequency of treatment discontinuation due to adverse effects Skin protection education vs no or minimal intervention | no estimate extracted | 1 study · 250 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |