Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Urology

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

Single‐dose, preoperative MMC‐EMDA vs single‐dose, postoperative MMC‐PD

Time to recurrence

Single‐dose, preoperative MMC‐EMDA probably leads to lower time to recurrence compared with single‐dose, postoperative MMC‐PD (moderate certainty).

1 finding from 1 review

Intravesical electromotive drug administration for non‐muscle invasive bladder cancer 2017 · Cochrane Headline outcomes only
HR 0.47 [0.32, 0.69]
1 study · 236 participants
Moderate

Single‐dose, preoperative MMC‐EMDA vs TURBT alone

Time to recurrence

Single‐dose, preoperative MMC‐EMDA probably leads to lower time to recurrence compared with TURBT alone (moderate certainty).

1 finding from 1 review

Intravesical electromotive drug administration for non‐muscle invasive bladder cancer 2017 · Cochrane Headline outcomes only
HR 0.4 [0.28, 0.57]
1 study · 233 participants
Moderate

Single‐dose intravesical chemotherapy instillation vs placebo or observation after nephroureterectomy

Time to bladder cancer recurrence (absolute effect size estimates based on recurrence rate at 12 months)

Single‐dose intravesical chemotherapy instillation may leads to lower time to bladder cancer recurrence (absolute effect size estimates… compared with placebo or observation after nephroureterectomy (low certainty).

1 finding from 1 review

Single‐dose intravesical chemotherapy after nephroureterectomy for upper tract urothelial carcinoma 2019 · Cochrane Headline outcomes only
HR 0.51 [0.32, 0.82]
2 studies · 311 participants
Low