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Evidence found and GRADE certainty

6 questions · 6 findings · 3 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 2 · 33.3%Moderate 2 · 33.3%High 0 · 0%

Tranexamic acid vs placebo/no treatment

Thromboembolic events · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage

Tranexamic acid showed no clear difference in thromboembolic events compared with placebo/no treatment (low certainty).

1 finding from 1 review

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs placebo or usual care

Thromboembolic events · Percutaneous nephrolithotomy

Topical TXA showed no clear difference in thromboembolic events compared with no TXA (placebo or usual care) (moderate certainty).

1 finding from 1 review

Intervention not reported

Venous thromboembolic events (number of participants with at least one venous thromboembolic events) Time: 5‐week · adult women with advanced EOC undergoing cytoreductive surgery (one randomised trial available)

It is very uncertain whether the intervention changes venous thromboembolic events (number of participants with at least… (very low certainty).

1 finding from 1 review

Intervention not reported

Arterial thromboembolic events (number of participants with at least one venous thromboembolic events) Time: 5‐week · adult women with advanced EOC undergoing cytoreductive surgery (one randomised trial available)

It is very uncertain whether the intervention changes arterial thromboembolic events (number of participants with at least… (very low certainty).

1 finding from 1 review