What do systematic reviews say?

Topical antibiotics with steroids vs topical antibiotics

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 395 participants
  Very low

Topical antibiotics with steroids vs topical antibiotics

It is very uncertain whether topical antibiotics with steroids changes suspected ototoxicity: dizziness/vertigo/balance compared with topical antibiotics alone (very low certainty).

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  RR 0.46 [0.04, 4.8]
  1 study · 52 participants
  Very low

Topical antibiotics vs placebo/no treatment

• Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 35 participants
  Very low

Topical antibiotics vs acetic acid

It is very uncertain whether topical antibiotics changes suspected ototoxicity compared with acetic acid (very low certainty).

• Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Very low

Topical quinolone vs povidone‐iodine

It is very uncertain whether topical antibiotics (quinolones) changes suspected ototoxicity compared with povidone‐iodine (very low certainty).

• Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 40 participants
  Very low

Topical antibiotics with steroids vs placebo/no treatment

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 123 participants
  Very low

Topical quinolone vs boric acid

The review found no eligible studies for this question.

• Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antibiotics vs no treatment or placebo on top of topical antibiotics

The review found no eligible studies for this question.

• Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antibiotics vs no treatment or placebo on top of topical antibiotics

It is very uncertain whether systemic antibiotics changes suspected ototoxicity ‐ measured at 10 days to 3 weeks compared with no treatment or placebo on top of topical antibiotics (very low certainty).

• Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  RR 3 [0.13, 71.92]
  3 studies · 250 participants
  Very low

Antibiotics vs no treatment or placebo on top of topical antiseptics

• Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 204 participants
  Very low

Topical quinolone vs intramuscular gentamicin

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 56 participants
  Very low

Topical quinolone vs quinolones

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 265 participants
  Very low

Intervention not reported

• Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 190 participants
  Very low

Quinolone vs aminoglycosides

• Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 352 participants
  Very low