Findings

What do systematic reviews say?

6 questions · 6 findings · 3 reviews · Urology

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 16.7%Low 3 · 50%Moderate 2 · 33.3%High 0 · 0%

Percutaneous nephrolithotripsy vs tubeless percutaneous nephrolithotripsy

Stone‐free rate

It is very uncertain whether percutaneous nephrolithotripsy changes stone‐free rate compared with tubeless percutaneous nephrolithotripsy (very low certainty).

1 finding from 1 review

Medical and surgical interventions for the treatment of urinary stones in children 2019 · Cochrane Headline outcomes only
RR 1.16 [0.88, 1.53]
1 study · 23 participants
Very low

Percutaneous nephrolithotripsy vs tubeless mini‐percutaneous nephrolithotripsy

Stone‐free rate

Percutaneous nephrolithotripsy showed no clear difference in stone‐free rate compared with tubeless mini‐percutaneous nephrolithotripsy (moderate certainty).

1 finding from 1 review

Medical and surgical interventions for the treatment of urinary stones in children 2019 · Cochrane Headline outcomes only
RR 1.03 [0.93, 1.14]
1 study · 70 participants
Moderate

Percutaneous nephrolithotomy vs retrograde intrarenal surgery

Stone‐free rate · adults with renal stones

Percutaneous nephrolithotomy may leads to higher stone‐free rate Assumed MCID: 5% compared with retrograde intrarenal surgery (low certainty).

1 finding from 1 review

Percutaneous nephrolithotomy versus retrograde intrarenal surgery for treatment of renal stones in adults 2023 · Cochrane Headline outcomes only
RR 1.13 [1.08, 1.18]
39 studies · 4088 participants
Low

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs placebo or usual care

Stone‐free rate · Percutaneous nephrolithotomy

Topical TXA showed no clear difference in stone‐free rate compared with no TXA (placebo or usual care) (low certainty).

1 finding from 1 review

Tranexamic acid for percutaneous nephrolithotomy 2023 · Cochrane Headline outcomes only
RR 1.07 [0.99, 1.17]
1 study · 400 participants
Low

Systemic TXA vs placebo or usual care

Stone‐free rate · Percutaneous nephrolithotomy

Systemic TXA showed no clear difference in stone‐free rate compared with no TXA (placebo or usual care) (low certainty).

1 finding from 1 review

Tranexamic acid for percutaneous nephrolithotomy 2023 · Cochrane Headline outcomes only
RR 1.11 [0.98, 1.27]
4 studies · 603 participants
Low

Shock wave lithotripsy vs mini‐percutaneous nephrolithotripsy

Stone‐free rate

Shock wave lithotripsy probably leads to lower stone‐free rate compared with mini‐percutaneous nephrolithotripsy (moderate certainty).

1 finding from 1 review

Medical and surgical interventions for the treatment of urinary stones in children 2019 · Cochrane Headline outcomes only
RR 0.88 [0.8, 0.97]
1 study · 212 participants
Moderate