Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

37 questions · 37 findings · 16 reviews

No studies found 10 · 27%GRADE not reported 1 · 2.7%Very low 13 · 35.1%Low 9 · 24.3%Moderate 4 · 10.8%High 0 · 0%

Surgical portosystemic shunts vs devascularisation with splenectomy

Serious adverse events · people with hepatosplenic schistosomiasis

It is very uncertain whether surgical portosystemic shunts changes serious adverse events compared with devascularisation with splenectomy (very low certainty).

1 finding from 1 review

Surgical interventions (exploration and decompression / external neurolysis, internal neurolysis, neurorrhaphy / direct repair, neuroma excision, anastomosis, autologous or allograft nerve grafting or tubulization) vs conservative interventions

Serious adverse events · Children and adolescents with femoral shaft fractures

Surgical interventions may leads to higher serious adverse events compared with conservative interventions (low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Serious adverse events · people with surgically‐induced remission in Crohn's disease

It is very uncertain whether azathioprine or 6‐mercaptopurine changes serious adverse events compared with 5‐aminosalicylic acid (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine vs anti TNF‐ɑ

Serious adverse events · people with surgically‐induced remission in Crohn's disease

It is very uncertain whether azathioprine or 6‐mercaptopurine changes serious adverse events compared with anti TNF‐α (very low certainty).

1 finding from 1 review