What do systematic reviews say?

Summary of findings table ‐ Systemic therapy vs control

• Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  Low

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery plus WBRT

• Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 14 participants
  Very low

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery

• Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1 participants
  Very low

Summary of findings table ‐ Systemic therapy vs control

• Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 208 participants
  Very low

CBT vs usual care

Cognitive‐behavioural therapy probably leads to higher health‐related quality of life Investigators measured health‐related… compared with usual care (moderate certainty).

• Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
  SMD 0.51 [0.19, 0.83]
  4 studies · 230 participants
  Moderate

Physical activity vs usual care

• Physical activity interventions for disease‐related physical and mental health during and following treatment in… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 230 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in health‐related quality of life (HRQOL) disease‐specific HRQOL (low certainty).

• Positive expiratory pressure therapy versus other airway clearance techniques for bronchiectasis 2017 · Cochrane Headline outcomes only
  no estimate extracted
  17 participants
  Low

Flutamide 250 mg once to b.i.d. vs spironolactone 100 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Spironolactone 100 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg to 7.5 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Metformin 500 mg to 2550 mg per day vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg vs spironolactone 100 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flutamide 250 mg b.i.d. vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found