Findings

What do systematic reviews say?

19 questions · 19 findings · 12 reviews · Haematology

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No studies found 15 · 78.9%GRADE not reported 2 · 10.5%Very low 1 · 5.3%Low 0 · 0%Moderate 0 · 0%High 1 · 5.3%

ATRA in addition to chemotherapy vs chemotherapy alone

Quality of life · adults with acute myeloid leukaemia (AML) (non‐acute promyelocytic leukaemia (APL))

The review found no eligible studies for this question.

1 finding from 1 review

Effects of all‐trans retinoic acid (ATRA) in addition to chemotherapy for adults with acute myeloid leukaemia (AML)… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Escalated BEACOPP vs chemotherapy including ABVD

Quality of life · Patients with early unfavourable or advanced stage HL

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of first‐line chemotherapy including escalated BEACOPP versus chemotherapy including ABVD for people with… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life · cancer patients receiving myelotoxic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life · cancer patients receiving myelotoxic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life ‐ not reported · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

The review found no eligible studies for this question.

1 finding from 1 review

Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated… 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life ‐ not reported · people with haematological disorders undergoing intensive chemotherapy or stem cell transplantation

The review found no eligible studies for this question.

1 finding from 1 review

Alternatives, and adjuncts, to prophylactic platelet transfusion for people with haematological malignancies… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Thrombopoietin mimetics vs placebo or usual care

Quality of life ‐ not reported · people with haematological disorders undergoing intensive chemotherapy or stem cell transplantation

The review found no eligible studies for this question.

1 finding from 1 review

Alternatives, and adjuncts, to prophylactic platelet transfusion for people with haematological malignancies… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Therapeutic or non‐prophylactic platelet transfusion vs prophylactic platelet transfusion

Quality of life ‐ not reported · patients with haematological disorders undergoing myelosuppressive chemotherapy or stem cell transplantation

1 finding from 1 review

A therapeutic‐only versus prophylactic platelet transfusion strategy for preventing bleeding in patients with… 2015 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Quality of life (0 to 3 months) · Adults with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem…

1 finding from 1 review

Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated… 2024 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 431 participants
Very low

Intervention not reported

Quality of life score ‐ not measured · patients with solid tumours with thrombocytopenia during chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Thrombopoietin receptor agonists for prevention and treatment of chemotherapy‐induced thrombocytopenia in patients… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life score ‐ not measured · patients with solid tumours without thrombocytopenia before chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Thrombopoietin receptor agonists for prevention and treatment of chemotherapy‐induced thrombocytopenia in patients… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life (better indicated by higher values) · people diagnosed with chemotherapy‐induced anemia

The intervention showed no clear difference in quality of life (better indicated by higher values) (high certainty).

1 finding from 1 review

The role of iron in the management of chemotherapy‐induced anemia in cancer patients receiving… 2016 · Cochrane Headline outcomes only
SMD 0.01
3 studies · 1124 participants
High

Summary of Findings Table ‐ Enoxaparin vs no enoxaparin

Quality of life ‐ not reported · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of Findings Table ‐ Antithrombin concentrates vs no antithrombin concentrates

Quality of life ‐ not reported · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life not reported · Patients with refractory/relapsed Hodgkin lymphoma

1 finding from 1 review

High‐dose chemotherapy followed by autologous stem cell transplantation for patients with relapsed/refractory Hodgkin… 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000)

Quality of life ‐ not reported · People with a haematological disorder

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic platelet transfusions with low‐dose schedule vs high‐dose schedule

Quality of life ‐ not reported · People with a haematological disorder

The review found no eligible studies for this question.

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic platelet transfusions with high‐dose schedule vs standard‐dose strategies

Quality of life ‐ not reported · People with a haematological disorder

The review found no eligible studies for this question.

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic platelet transfusions with low‐dose schedule vs prophylactic platelet transfusions with standard‐dose schedule

Quality of life ‐ not reported · People with a haematological disorder

The review found no eligible studies for this question.

1 finding from 1 review

Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found