Findings

What do systematic reviews say?

100 questions · 116 findings · 41 reviews

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No studies found 48 · 41.4%GRADE not reported 21 · 18.1%Very low 12 · 10.3%Low 16 · 13.8%Moderate 17 · 14.7%High 2 · 1.7%

Diaphragmatic breathing vs no breathing exercises

Health‐related quality of life Change in total score of St George Respiratory Questionnaire · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Moderate

Dental caries vs Caries-free controls

Oral health-related quality of life · Indian children aged 3-5 years

In children aged 3-5 years, early childhood caries was significantly associated with poorer OHRQoL (narrative; 3 studies); ungraded.

1 finding from 1 review

Impact of oral conditions on oral health-related quality of life among Indians- a systematic review and Meta-analysis. 2023 All outcomes
India; community-based and institutional settings across multiple states · Children 3-5 years (ECOHIS/Michigan, continuous)
Subgroup children 3-5 years (continuous, ECOHIS/Michigan): early childhood caries significantly associated with poorer OHRQoL (Singh N 2020, Ghanghas 2019, Jaggi 2019); not pooled.
3 studies
GRADE not reported

Action plan vs usual care

Quality of life St George's Respiratory Questionnaire (SGRQ) score · acute exacerbations of chronic obstructive pulmonary disease

1 finding from 1 review

Action plans with brief patient education for exacerbations in chronic obstructive pulmonary disease 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1009 participants
Moderate

Mepolizumab 100 mg vs placebo

Change in SGRQ total score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1285 participants
Moderate

Benralizumab 10 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 680 participants
Moderate

Benralizumab 30 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1333 participants
Moderate

Benralizumab 100 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1351 participants
High

Mepolizumab 300 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 451 participants
Moderate

Mepolizumab 100 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 911 participants
Moderate

MX exercise training vs control

HRQL FIQ Total. Scale from 0 to 100; high scores indicate worse quality of life Median length of interventions: 12 weeks · patients with fibromyalgia

1 finding from 1 review

Mixed exercise training for adults with fibromyalgia 2019 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 610 participants
Moderate

Intervention not reported

Disease‐specific quality of life QUALEFFO‐41 total score Scale from 0 to 100 Lower scores indicate better quality of life · individuals with osteoporotic vertebral fracture

1 finding from 1 review

Exercise for improving outcomes after osteoporotic vertebral fracture 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 109 participants
Very low

Intervention not reported

General health‐related quality of life: SF‐36 physical component score (range 0 to 100; higher score = better health state) at 2 years · Adults with acute anterior cruciate ligament (ACL) injuries (young, active individuals)

1 finding from 1 review

Surgical versus conservative interventions for treating anterior cruciate ligament injuries 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 121 participants
Low

Escitalopram vs placebo

Quality of life at 3 months ‐ not measured · adults experiencing acute traumatic stress symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pursed lip breathing vs no breathing exercises

Health‐related quality of life Dyspnoea domain of Hiratsuka scale Scores range from 0 to 100, with lower scores indicating less shortness of breath · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 60 participants
Low

Intervention not reported

Health‐related quality of life (disease‐specific) Scale from 0 to 100; lower score indicates better HRQoL. SGRQ total score consists of weighted scores from 3 domains · individuals with stable bronchiectasis

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Intervention not reported

Health‐related quality of life (health status) COPD Assessment Tool. Scale from 0 to 5; higher score indicates worse HRQoL Contains 10 questions with 5‐point Likert scale · individuals with stable bronchiectasis

The intervention showed no clear difference in health‐related quality of life (health status) COPD Assessment Tool.… (low certainty).

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Low

Ventilation feedback training plus exercise vs exercise

Health‐related quality of life (Change in CRQ Dyspnoea) CRQ · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 73 participants
Moderate

Intervention not reported

Health‐related quality of life (cough‐specific) Leicester Cough Questionnaire Scale from 0 to 133; higher score indicates better HRQoL. Contains 19 questions from 3 domains on a Likert scale · individuals with stable bronchiectasis

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Intervention not reported

Global quality of life FLIC total score (Blanchard 1996), FACT‐G total score (Northouse 2007). Additional studies (reported in comments section): FACT‐B physical functioning subscale (Baucom 2009). EPIC multiple subscales and overall scores (Campb... · individuals with cancer (patients)

1 finding from 1 review

Psychosocial interventions for informal caregivers of people living with cancer 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 292 participants
Very low

Intervention not reported

Global quality of life FLIC total score (Blanchard 1996), EORTC‐QLQ‐C30 global health status score (Ledderer 2013), FACT‐G total score (Northouse 2007). Additional study (reported in comments section): FACT‐B physical functioning subscale (Baucom ... · individuals with cancer (patients)

1 finding from 1 review

Psychosocial interventions for informal caregivers of people living with cancer 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 294 participants
Low