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Evidence found and GRADE certainty

259 questions · 296 findings · 91 reviews

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No studies found 111 · 37.5%GRADE not reported 130 · 43.9%Very low 30 · 10.1%Low 8 · 2.7%Moderate 12 · 4.1%High 5 · 1.7%

Atraumatic restorative treatment vs placebo

Oral health-related quality of life · Children with dental caries

ART and placebo did not differ for oral health-related quality of life, based on an indirect network estimate with no direct trials (MD -0.01, 95% CI -0.40 to 0.38; ungraded).

3 findings from 1 review

Placebo vs Silver diamine fluoride

Oral health-related quality of life · Children with dental caries

The direct estimate found no statistically significant difference in oral health-related quality of life between placebo and silver diamine fluoride.

2 findings from 1 review

Atraumatic restorative treatment plus fluoride varnish vs Silver diamine fluoride plus fluoride varnish

Oral health-related quality of life · Children with dental caries

The direct estimate found no statistically significant difference in oral health-related quality of life between atraumatic restorative treatment plus fluoride varnish and silver diamine fluoride plus fluoride varnish.

2 findings from 1 review

Atraumatic restorative treatment vs Silver diamine fluoride

Oral health-related quality of life · Children with dental caries

The network estimate found no statistically significant difference in oral health-related quality of life between atraumatic restorative treatment and silver diamine fluoride.

2 findings from 1 review

Clinical examination with 24-month recall vs Clinical examination with 12-month recall

Oral health-related quality of life · Regular-attending primary-care dental patients aged 3, 16 or 18 years at entry (aged up to 20; low caries risk)

The review found no eligible studies for this question.

1 finding from 1 review

Any form of one-to-one oral hygiene advice (OHA) vs No OHA

Patient-reported changes in knowledge, attitudes and quality of life · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review

Safe housing / favorable household conditions vs Unsafe housing / poor household conditions

Oral health-related quality of life · Adolescents (10-19 years)

Safe housing and favorable household conditions are associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    having parents who can provide dental care and safe housing are positive predictors for OHRQoL. Socioeconomic factors related to the area of residence, satisfaction with oral health and dental care were shown to be…
    Studies not reported
    GRADE not reported

Traumatic dental injury (dental trauma) vs No dental trauma

Oral health-related quality of life · Adolescents (10-19 years)

Complicated traumatic dental injuries (pulp exposure or tooth darkening) worsen OHRQoL in adolescents, while uncomplicated injuries show little impact (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    The impact of dental trauma sequelae on OHRQoL in adolescents was observed in five systematic reviews [31-35]. The studies show that uncomplicated traumatic injuries do not have a negative impact on the OHRQoL of…
    5 studies
    GRADE not reported

Operative treatment of dental caries lesions vs No caries treatment

Oral health-related quality of life · Adolescents (10-19 years)

Operative treatment of caries lesions has a positive effect on OHRQoL in adolescents, though the included evidence was of low quality (narrative synthesis; no pooled estimate or GRADE rating by the umbrella review).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    the operative treatment of caries lesions has a positive effect on OHRQoL, despite the low quality of evidence [9]. There is low evidence that the OHRQoL of children and adolescents improved following caries…
    Studies not reported
    GRADE not reported

Periodontal disease (severe periodontitis) vs Individuals without periodontal disease (by LOA)

Oral health-related quality of life · Adolescents (10-19 years)

Severe periodontal disease is associated with worse OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review

Dental caries vs Absence/lower severity of dental caries

Oral health-related quality of life · Adolescents (10-19 years)

Dental caries is associated with worse OHRQoL in adolescents, with greater severity linked to greater impact (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    The impact of dental caries on OHRQoL was addressed in five systematic reviews [9, 26, 34, 36, 37]. Three articles report that the greater the severity of the carious lesion, the worse the impact on OHRQoL in…
    5 studies
    GRADE not reported

Higher family income / socioeconomic status vs Lower income / worse socioeconomic status

Oral health-related quality of life · Adolescents (10-19 years)

Higher family income / better socioeconomic status is associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Adolescents from families with higher incomes and higher levels of maternal education have better OHRQoL scores [34]. Worse oral health status, older age, female sex and worse socioeconomic status were significantly…
    Studies not reported
    GRADE not reported

Completed orthodontic treatment vs Untreated / never received orthodontic treatment

Oral health-related quality of life · Adolescents (10-19 years)

Completing orthodontic treatment is associated with improved OHRQoL in adolescents (narrative synthesis; included reviews report low-to-moderate certainty; no pooled estimate or GRADE rating by the umbrella review).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Adolescents who had never received orthodontic treatment had a greater impact on quality of life compared to patients who had already completed treatment [34, 40, 44-46]. Orthodontic treatment during childhood or…
    Studies not reported
    GRADE not reported