Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

630 questions · 634 findings · 285 reviews

No studies found 316 · 49.8%GRADE not reported 40 · 6.3%Very low 95 · 15%Low 111 · 17.5%Moderate 60 · 9.5%High 12 · 1.9%

Pilocarpine vs no treatment/placebo

Quality of life (McMaster HNRQ, 1-7 scale) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

It is very uncertain whether pilocarpine changes quality of life (McMaster HNRQ, 1-7 scale) compared with no treatment/placebo (very low certainty).

1 finding from 1 review

Antimicrobial lozenge vs placebo

Quality of life and other oral related symptoms · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review