Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

13 questions · 14 findings · 5 reviews · Metabolic and Endocrine Disorders

No studies found 8 · 57.1%GRADE not reported 0 · 0%Very low 4 · 28.6%Low 1 · 7.1%Moderate 1 · 7.1%High 0 · 0%

Surgery vs no surgery

Health related quality of life the Uniscale and the Symptom Distress Scale (SDS); Better indicated by lower values · participants with obesity
1 finding from 1 review

Surgery vs Pharmacological therapy

Health‐related quality of life Mean AcroQoL score (0‐100) · adults with growth‐hormone secreting pituitary adenomas

Surgery alone showed no clear difference in health‐related quality of life Mean AcroQoL score (0‐100) compared with pharmacological therapy alone (low certainty).

1 finding from 1 review

Intervention not reported

Health‐related quality of life (CHQ (8 subscores); scale 0 to 100, where 0 indicates the worst possible health state and 100 the best possible health state)c Physical functioning Change in health · children and adolescents with obesity

It is very uncertain whether the intervention changes health‐related quality of life (CHQ (8 subscores); scale 0 to 100,… (very low certainty).

1 finding from 1 review