Findings

What do systematic reviews say?

37 questions · 37 findings · 24 reviews

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No studies found 8 · 21.6%GRADE not reported 3 · 8.1%Very low 10 · 27%Low 9 · 24.3%Moderate 6 · 16.2%High 1 · 2.7%

WBRT with radiosensitisers (radiosen) vs WBRT

Quality of lifeNo. of participants: 271(2 RCTs) · patients with newly diagnosed multiple brain metastases

1 finding from 1 review

Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Radiosurgery alone vs WBRT and radiosurgery

Quality of lifeNo. of participants: 271(2 RCTs) · patients with newly diagnosed multiple brain metastases

1 finding from 1 review

Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Summary of findings table ‐ Daratumumab plus standard therapy vs usual care

Health‐related quality of life European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ‐C30). Scale from: 0 to 100 (a higher score means a better outcome) · people with newly diagnosed multiple myeloma ineligible for transplant

1 finding from 1 review

Daratumumab and antineoplastic therapy versus antineoplastic therapy only for adults with newly diagnosed multiple… 2024 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1096 participants
Low

TENS vs sham

Quality of life · chronic back pain in MS

1 finding from 1 review

Non‐pharmacological interventions for chronic pain in multiple sclerosis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Very low

Ai Chi Exercises vs sham

Quality of life · chronic musculoskeletal pain in people with MS

1 finding from 1 review

Non‐pharmacological interventions for chronic pain in multiple sclerosis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 73 participants
Very low

Intervention not reported

Quality of life ‐ intermediateMSIS, MSQOL, SF‐36, SF‐12, SWLS, EQ‐5D‐5La · people with multiple sclerosis

1 finding from 1 review

Memory rehabilitation for people with multiple sclerosis 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 683 participants
High

Intervention not reported

Change in quality of life Measures: QWB, HAQUAMS, MSIS‐29, SF‐36, LMSQOLS, · People with multiple sclerosis

1 finding from 1 review

Telerehabilitation for persons with multiple sclerosis 2015 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 392 participants
Low

Palliative care vs usual care

Health‐related quality of life Assessed by: SeiQoL‐DW (higher scores mean better quality of life) · adults with multiple sclerosis Interventions: immunosuppressive and immunomodulatory drugs Comparator: placebo Outcome: withdrawals due to…

1 finding from 1 review

Palliative care interventions for people with multiple sclerosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Very low

Intervention not reported

Health‐related quality of life · older patients using at least 4 regular prescription medications (and/or their carers)

1 finding from 1 review

Interventions for improving medication‐taking ability and adherence in older adults prescribed multiple medications 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Intervention not reported

Health‐related quality of life · older patients using at least 4 regular prescription medications (and/or their carers)

1 finding from 1 review

Interventions for improving medication‐taking ability and adherence in older adults prescribed multiple medications 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Health‐related quality of life · older patients using at least 4 regular prescription medications (and/or their carers)

1 finding from 1 review

Interventions for improving medication‐taking ability and adherence in older adults prescribed multiple medications 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Multifactorial interventions vs exercise

Health‐related quality of life · Older people living in the community

The review found no eligible studies for this question.

1 finding from 1 review

Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Multifactorial interventions vs usual care or attention control

Health‐related quality of life · Older people living in the community

1 finding from 1 review

Multifactorial and multiple component interventions for preventing falls in older people living in the community 2018 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 2373 participants
Low

Reflexology vs sham

Improvement in quality of life · chronic pain in MS

1 finding from 1 review

Non‐pharmacological interventions for chronic pain in multiple sclerosis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 71 participants
Very low

Disability (developmental, intellectual, or sensory) vs Persons without disabilities

Oral health-related quality of life · Persons with disabilities (children and adults with autism, Down syndrome, cerebral palsy, hearing impairment, or multiple disabilities)…

Persons with disabilities in Saudi Arabia report poorer overall oral health-related quality of life and greater oral-health impact than those without disabilities, synthesized narratively without a pooled estimate (ungraded).

1 finding from 1 review

Disabilities and Disparities in Oral Health-Related Quality of Life: A Systematic Review and Meta-Analysis in Saudi… 2024 All outcomes
Cross-sectional · Autism centres, dental hospital, disability centres, hospital, and public schools across Saudi Arabia (Riyadh, Jeddah, Qassim, Abha)
Narrative synthesis (no pooled estimate). PWDs reported reduced functional, emotional, and social well-being and greater oral-health impact on quality of life. AlJameel 2021 (Down syndrome): 34.9% of children and 46%…
Studies not reported
GRADE not reported

Summary of findings table ‐ Cannabis vs placebo

Health‐related quality of life. Mean change from baseline · health problem or population

1 finding from 1 review

Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis 2022 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1942 participants
Low

Telephone‐Delivered Education Group vs sham

Improvement in pain, self efficacy,patient activation, health‐related quality of life, social role satisfaction,resilience,positive and negative affect · chronic pain in MS

1 finding from 1 review

Non‐pharmacological interventions for chronic pain in multiple sclerosis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 163 participants
Very low