Probing pocket depth · Adults with periodontitis (chronic and aggressive)
Azithromycin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
3 findings from 1 review
MD -0.57 [-1.08, -0.07]
6 studies · 216 participants
GRADE not reported
MD -0.77 [-2.33, 0.79]
2 studies · 110 participants
Very low
MD -0.60 [-1.02, -0.18]
7 studies · 258 participants
GRADE not reported
Probing pocket depth · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether metronidazole + SRP changes probing pocket depth compared with SRP (very low certainty).
3 findings from 1 review
MD -1.11 [-2.84, 0.61]
2 studies · 47 participants
Very low
MD -0.59 [-0.95, -0.23]
4 studies · 94 participants
GRADE not reported
MD -0.10 [-0.37, 0.16]
4 studies · 108 participants
GRADE not reported
Probing pocket depth · Adults with aggressive periodontitis
Doxycycline + SRP showed no clear difference in probing pocket depth compared with SRP; GRADE not reported.
3 findings from 1 review
MD 0.10 [-0.29, 0.50]
2 studies · 43 participants
GRADE not reported
MD -1.00 [-1.78, -0.22]
1 study · 22 participants
Very low
MD -0.43 [-0.88, 0.01]
3 studies · 65 participants
GRADE not reported
Probing pocket depth · Adults with periodontitis (chronic and aggressive)
Amoxicillin + metronidazole + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
3 findings from 1 review
MD -0.47 [-0.68, -0.26]
6 studies · 215 participants
GRADE not reported
MD -0.18 [-0.33, -0.04]
15 studies · 562 participants
GRADE not reported
MD -0.30 [-0.42, -0.18]
2 studies · 389 participants
Very low
Probing pocket depth · Adults with aggressive periodontitis
Doxycycline + SRP showed no clear difference in probing pocket depth compared with metronidazole + SRP; GRADE not reported.
3 findings from 1 review
MD 0.38 [0.00, 0.76]
3 studies · 75 participants
GRADE not reported
MD 1.00 [0.30, 1.70]
1 study · 27 participants
Very low
MD -0.16 [-0.56, 0.24]
2 studies · 49 participants
GRADE not reported
Probing pocket depth · Adults with aggressive periodontitis
Clindamycin + SRP showed no clear difference in probing pocket depth compared with metronidazole + SRP; GRADE not reported.
3 findings from 1 review
MD -0.14 [-0.82, 0.54]
1 study · 26 participants
GRADE not reported
MD -0.10 [-0.79, 0.59]
1 study · 26 participants
GRADE not reported
MD 0.20 [-0.38, 0.78]
1 study · 26 participants
Very low
Probing pocket depth · Adults with chronic periodontitis
Amoxicillin + clavulanate + SRP showed no clear difference in probing pocket depth compared with SRP; GRADE not reported.
3 findings from 1 review
MD 0.00 [-0.19, 0.19]
1 study · 21 participants
GRADE not reported
MD 0.10 [-0.17, 0.37]
1 study · 21 participants
Very low
MD 0.20 [-0.02, 0.42]
1 study · 21 participants
GRADE not reported
Probing pocket depth · Adults with aggressive periodontitis
The review found no eligible studies for this question.
2 findings from 1 review
Probing pocket depth · Adults with aggressive periodontitis
Doxycycline + SRP showed no clear difference in probing pocket depth compared with amoxicillin + metronidazole + SRP; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults with aggressive periodontitis
Amoxicillin + metronidazole + SRP led to lower probing pocket depth compared with clarithromycin + SRP; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults with aggressive periodontitis
It is very uncertain whether clindamycin + SRP changes probing pocket depth compared with doxycycline + SRP (very low certainty).
3 findings from 1 review
MD -0.80 [-1.58, -0.02]
1 study · 23 participants
Very low
MD 0.20 [-0.36, 0.76]
1 study · 23 participants
GRADE not reported
MD -0.40 [-1.14, 0.34]
1 study · 23 participants
GRADE not reported
Probing pocket depth · Adults with chronic periodontitis
Levofloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults with aggressive periodontitis
It is very uncertain whether clindamycin + SRP changes probing pocket depth compared with SRP (very low certainty).
3 findings from 1 review
MD -1.80 [-2.47, -1.13]
1 study · 21 participants
Very low
MD -1.10 [-1.94, -0.26]
1 study · 21 participants
GRADE not reported
MD 0.10 [-0.55, 0.75]
1 study · 21 participants
GRADE not reported
Probing pocket depth · Adults with chronic periodontitis
Moxifloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults with periodontitis (chronic and aggressive)
Clarithromycin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults with periodontitis (chronic and aggressive)
Metronidazole + SRP showed no clear difference in probing pocket depth compared with amoxicillin + metronidazole + SRP; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults with aggressive periodontitis
Amoxicillin + clavulanate + SRP showed no clear difference in probing pocket depth compared with tetracycline + SRP; GRADE not reported.
1 finding from 1 review
MD -0.40 [-1.11, 0.31]
1 study · 8 participants
GRADE not reported
Probing pocket depth · Adults with chronic periodontitis
Cefixime + SRP showed no clear difference in probing pocket depth compared with SRP; GRADE not reported.
1 finding from 1 review
Probing pocket depth · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
It is very uncertain whether SPT performed by non-specialist clinicians (general dental… changes probing pocket depth (mm) compared with SPT performed by specialists (specialist practice) (very low certainty).
1 finding from 1 review
Probing pocket depth · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)
It is very uncertain whether photodynamic therapy plus mechanical debridement changes probing pocket depth (mm) compared with mechanical debridement alone (very low certainty).
1 finding from 1 review