Question · asked by 1 review

Levofloxacin + SRP vs SRP: Probing pocket depth

Population
Adults with chronic periodontitis
Intervention
Levofloxacin + SRP
Comparison
SRP
Outcome
Probing pocket depth

Levofloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.

What each review found

Include earlier review versions
No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Levofloxacin + SRP vs SRP
Probing pocket depth · Adults with chronic periodontitis · Intermediate-term (> 3 months to < 1 year)
Levofloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane All outcomes
MD -1.23 [-1.46, -1.00]2 studies · 131 participantsGRADE not reported
Levofloxacin + SRP vs SRP
Probing pocket depth · Adults with chronic periodontitis · Short-term (≤ 3 months)
Levofloxacin + SRP led to lower probing pocket depth compared with SRP; GRADE not reported.
Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis (2020) · Cochrane All outcomes
MD -1.09 [-1.33, -0.85]2 studies · 131 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis
2020 · Cochrane All outcomes
2020-03Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.