Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

32 questions · 32 findings · 7 reviews · Stroke

No studies found 15 · 46.9%GRADE not reported 3 · 9.4%Very low 11 · 34.4%Low 2 · 6.3%Moderate 0 · 0%High 1 · 3.1%

Pharmacological interventions vs placebo

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether pharmacological interventions changes depression: meeting study criteria for depression at end of… compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke

It is very uncertain whether pharmacological interventions changes depression: < 50% reduction in scale scores at end of treatment… compared with placebo (very low certainty).

1 finding from 1 review

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: meeting study criteria for depression at end of · people with depression after stroke

Pharmacological intervention and non‐invasive brain stimulation… may leads to lower depression: meeting the criteria for depression at end of treatment… compared with a pharmacological intervention and sham stimulation or usual care… (low certainty).

1 finding from 1 review

Psychological therapy vs usual care or attention control

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether psychological therapy changes depression: meeting study criteria for depression at end of… compared with usual care and/or attention control (very low certainty).

1 finding from 1 review

Non‐invasive brain stimulation vs usual care with or without sham interventions

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether non‐invasive brain stimulation changes depression: meeting study criteria for depression at end of… compared with sham non‐invasive brain stimulation and/or usual care (very low certainty).

1 finding from 1 review