Findings

What do systematic reviews say?

19 questions · 20 findings · 12 reviews

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No studies found 4 · 20%GRADE not reported 2 · 10%Very low 7 · 35%Low 4 · 20%Moderate 3 · 15%High 0 · 0%

Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone

Pain · children and young people with JIA

The review found no eligible studies for this question.

1 finding from 1 review

Methotrexate for juvenile idiopathic arthritis 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tramadol vs paracetamol

Pain · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Tramadol vs placebo

Pain · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 3972 participants
Moderate

Tramadol vs NSAIDs

Pain · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 952 participants
Moderate

Tramadol vs other opioids

Pain · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 411 participants
Moderate

Acupuncture as an addition to the routine primary care that trial participants were receiving from their physicians vs routine primary physician care alone

Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · patients with hip osteoarthritis

1 finding from 1 review

Acupuncture for hip osteoarthritis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 137 participants
Low

HAART regimen + topical treatment vs HAART alone

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Topical treatments for HIV‐related oral ulcers 2012 · Cochrane All outcomes
No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
0 studies
No studies found

Summary of findings ‐ Exercise alone vs exercise plus electrophysical modality

Pain · participants with haemophilia

The review found no eligible studies for this question.

1 finding from 1 review

Exercise for haemophilia 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

LongoVital (herbal component alone) vs placebo

Number of days of pain (monthly average) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

LongoVital (herbal component alone) showed no clear difference in number of days of pain (monthly average) compared with placebo; GRADE not reported.

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
4 to 6 months
MD -3.80 [-9.39, 1.79]
1 study · 50 participants
GRADE not reported

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

Pain · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

TENS with exercise vs exercise

Participant‐reported pain relief of 30% or greater · adults with fibromyalgia

1 finding from 1 review

Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

TENS with exercise vs exercise

Participant‐reported pain relief of 50% or greater · adults with fibromyalgia

1 finding from 1 review

Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs IM morphine

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Acupuncture as an addition to patient education vs education alone

Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · patients with hip osteoarthritis

1 finding from 1 review

Acupuncture for hip osteoarthritis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
GRADE not reported

Laxative plus bulking agent vs laxative alone

Pain or straining on defecation · postpartum women who underwent surgical repair of third degree perineal tears

1 finding from 1 review

Interventions for preventing postpartum constipation 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 147 participants
Very low

Back school + other treatment vs other treatment alone

Pain (long‐term) VAS. Scale from: 0 to 10. · participants with acute or subacute low‐back pain

1 finding from 1 review

Back schools for acute and subacute non‐specific low‐back pain 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 141 participants
Very low

Back school + other treatment vs other treatment alone

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · participants with acute or subacute low‐back pain

2 findings from 1 review

Back schools for acute and subacute non‐specific low‐back pain 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 156 participants
Very low
Back schools for acute and subacute non‐specific low‐back pain 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 140 participants
Very low

Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty

Pain The Hospital for Special Surgrery 100‐point scoring system. Scale from: 0 to 30 (higher is better). · Patients with rheumatoid shoulder

1 finding from 1 review

Surgical interventions for the rheumatoid shoulder 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs lidocaine intraperitoneal instillation alone

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low