Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

15 questions · 17 findings · 5 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 6 · 35.3%Low 10 · 58.8%Moderate 1 · 5.9%High 0 · 0%

Gonadotropins with GnRH agonists vs gonadotropins alone

Multiple pregnancy rate · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether gonadotropins with GnRH agonists changes multiple pregnancy rate per couple compared with gonadotropins alone (very low certainty).

1 finding from 1 review

Gonadotropins with GnRH antagonist vs gonadotropins alone

Multiple pregnancy rate · intrauterine insemination (IUI) in women with infertility

Gonadotropins with GnRH antagonist showed no clear difference in multiple pregnancy rate per couple compared with gonadotropins alone (moderate certainty).

1 finding from 1 review

Gonadotrophins with anti‐oestrogens vs gonadotropins alone

Multiple pregnancy rate · intrauterine insemination (IUI) in women with infertility

Gonadotrophins with anti‐oestrogens showed no clear difference in multiple pregnancy rate per couple compared with gonadotropins alone (low certainty).

1 finding from 1 review

Aromatase inhibitors with gonadotropins vs anti‐oestrogens with gonadotropins

Multiple pregnancy rate · intrauterine insemination (IUI) in women with infertility

Aromatase inhibitors with gonadotropins showed no clear difference in multiple pregnancy rate per couple compared with anti‐oestrogens with gonadotropins (low certainty).

1 finding from 1 review

IUI in a stimulated cycle vs TI or expectant management

Multiple pregnancy rate · participants with unexplained subfertility

IUI in a stimulated cycle showed no clear difference in multiple pregnancy rate per couple compared with TI or expectant management (low certainty).

2 findings from 1 review

IUI in a natural cycle vs TI or expectant management

Multiple pregnancy rate · participants with unexplained subfertility

IUI in a natural cycle showed no clear difference in multiple pregnancy rate per couple compared with TI or expectant management (low certainty).

2 findings from 1 review