Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

111 questions · 118 findings · 48 reviews

No studies found 32 · 27.1%GRADE not reported 0 · 0%Very low 38 · 32.2%Low 36 · 30.5%Moderate 11 · 9.3%High 1 · 0.8%

Human menopausal gonadotrophin or highly purified human menopausal gonadotrophin vs urinary follicle stimulating hormone

Multiple pregnancy rate · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether human menopausal gonadotrophin or highly purified human menopausal… changes incidence of multiple pregnancy (per woman) compared with urinary follicle stimulating hormone (very low certainty).

1 finding from 1 review

Oestrogen vs no pretreatment

Multiple pregnancy rate · ovarian stimulation protocols for women undergoing ART

The review found no eligible studies for this question.

2 findings from 1 review

IVF vs unstimulated IUI

Multiple pregnancy rate · women with unexplained subfertility

It is very uncertain whether IVF changes multiple pregnancy rate per woman randomised compared with unstimulated IUI (very low certainty).

1 finding from 1 review

Intervention not reported

Multiple pregnancy ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether the intervention changes multiple pregnancy ‐ Clomiphene citrate 5 days versus clomiphene… (very low certainty).

1 finding from 1 review

Routine/revealed vs selective/concealed ultrasound

Detection of multiple pregnancy by 24 to 26 weeks' gestation (number NOT detected) · Fetal ultrasound assessment before 24 weeks' gestation

Routine/revealed probably leads to lower detection of multiple pregnancy by 24 to 26 weeks' gestation (number… compared with selective/concealed ultrasound (moderate certainty).

1 finding from 1 review