Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Modified bovine minced lung surfactant extract vs porcine minced lung surfactant extract

Mortality before hospital discharge · Preterm infants for treatment of RDS

Modified bovine minced lung surfactant extract probably leads to higher mortality prior to hospital discharge (from any cause) compared with porcine minced lung surfactant extract (moderate certainty).

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
RR 1.44 [1.04, 2]
9 studies · 901 participants
Moderate

Modified bovine minced lung surfactant extract vs porcine lung lavage surfactant

Mortality before hospital discharge · Preterm infants for treatment of RDS

Modified bovine minced lung surfactant extract showed no clear difference in mortality prior to hospital discharge (from any cause) compared with porcine lung lavage surfactant (low certainty).

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
RR 1.1 [0.6, 1.99]
1 study · 44 participants
Low