Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews · Anaesthesia

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Continuation vs discontinuation of antiplatelet therapy

Mortality within the longest · adults undergoing non‐cardiac surgery

Continuation showed no clear difference in all‐cause mortality (at longest compared with discontinuation of antiplatelet therapy (low certainty).

1 finding from 1 review

Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing… 2018 · Cochrane Headline outcomes only
RR 1.21 [0.34, 4.27]
5 studies · 659 participants
Low

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Mortality within the longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

It is very uncertain whether pulmonary artery perfusion with blood changes all‐cause mortality within longest compared with no perfusion during cardiopulmonary bypass (very low certainty).

1 finding from 1 review

Pulmonary artery perfusion versus no perfusion during cardiopulmonary bypass for open heart surgery in adults 2018 · Cochrane Headline outcomes only
Peto OR 1.78 [0.43, 7.4]
4 studies · 210 participants
Very low

Perioperative restrictive fluid therapy vs goal‐directed fluid therapy

Mortality within the longest · adults receiving intravenous fluids while undergoing major non‐cardiac surgery

It is very uncertain whether perioperative restrictive fluid therapy changes all‐cause mortality (during longest compared with goal‐directed fluid therapy (very low certainty).

1 finding from 1 review

Perioperative restrictive versus goal‐directed fluid therapy for adults undergoing major non‐cardiac surgery 2019 · Cochrane Headline outcomes only
RD 0.03 [0, 0.06]
6 studies · 544 participants
Very low